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April is Parkinson’s Disease Awareness month, and on this episode of Managed Care Cast, we take a look at the Parkinson's Progression Markers Initiative (PPMI), a study from the Michael J. Fox Foundation for Parkinson's Research (MJFF). The multicenter, international study aims to end Parkinson disease, which is expected to double worldwide by 2040, to more than 14 million people.

A recent review found that periodontitis is associated with mild to moderate obstructive sleep apnea (OSA).

A federal judge revokes the federal mask requirement for public transit; Janssen settles it opioid-related lawsuit with West Virginia for $99 million; states are restricting abortion training for medical students and residents.

A recent study found that a composite end point developed by the researchers gave a single and simultaneous measurement of the overall benefit of treatment for paroxysmal nocturnal hemoglobinuria (PNH).

Investigators said these differences might help explain why some patients have better outcomes than others with combination immune checkpoint blockades.

Expression of the chemokine receptor was linked with better overall survival.

Florida Cancer Specialists & Research Institute (FCS) was ranked at the top among the 126 oncology practices participating in the Oncology Care Model across the country.

The shift to a value-based care platform through the Oncology Care Model was shown to stimulate a cost-effective, value-based platform for care delivery for FCS patients.

As more bacterial DNA sequences are identified, the computational challenges associated with whole-genome sequencing have researchers looking to other potential methods of tracking and understanding differences in bacterial pathogens such as Clostridioides difficile.

A recently published case study by Florida Cancer Specialists & Research Institute showcased the practice’s multi-year track record of delivering savings as a participant in the Oncology Care Model (OCM) when compared with OCM and non-OCM practices nationally.

Several modifiable lifestyle factors were associated with moderate to severe atopic dermatitis in a patient cohort from the Netherlands, including smoking, alcohol consumption, and stress.

A recent study found that primary care physicians (PCPs) and pulmonologists differ in their treatment methods and reference to guidelines when treating patients with chronic obstructive pulmonary disease (COPD).

Marc-Andre Cornier, MD, professor and director of the Division of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, discusses factors that could worsen US obesity rates.

Dexter Shurney, MD, MBA, MPH, chief health equity, diversity, and inclusion officer and chief medical officer at Adventist Health, discusses the concept of "food as medicine," which he will be explaining further at the National Association of Managed Care Physicians (NAMCP) Spring Managed Care Forum.

Complete with business, health management, and oncology tracks, sessions at the National Association of Managed Care Physicians (NAMCP) Spring Managed Care Forum will focus on a variety of topics.

Pacritinib is now included as a recommended treatment for myeloproliferative neoplasms with specificity for JAK2 and IRAK1 in the latest National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines.

The FDA is increasing oversight of e-cigarettes and similar products that use synthetic nicotine; a lawsuit is brought over Philadelphia's reinstated mask mandate; a study shows drinking water may lower risk of heart failure.

Patients may have unrealistic expectations of how a new treatment or procedure may help them, and the conversation between the patient and physician is crucial for setting expectations, explained Robert G. Fante, MD, FACS, president of the American Society of Ophthalmic Plastic & Reconstructive Surgery and facial plastic surgeon and cosmetic surgeon, Fante Eye & Face Centre in Denver, Colorado.

Stephen M. Schleicher, MD, MBA, chief medical officer, Tennessee Oncology, previews the Nashville meeting of The American Journal of Managed Care®'s Institute for Value-Based Medicine® (IVBM), co-hosted by Tennessee Oncology.

This study investigated long-term cardiac-related mortality as it relates to incidence of perioperative adverse cardiac events (excluding death) in the first 30 days after surgery among a short of patients who underwent non–cardiac-related surgery.

Addressing the opioid crisis will require a strong, multifaceted approach that includes efforts to prevent addiction before it begins. By passing the NOPAIN Act, Congress can seize the win-win opportunity to reduce unnecessary exposure to opioids, while protecting—and expanding—a patient’s right to choose their own care.

Davey Daniel, MD, chief medical officer, OneOncology, speaks on the knowledge, infrastructure, and payer-related barriers that are limiting the use of genomic testing in the management of patients with lung cancer.

Research shows that only 1.05% of US emergency department (ED) visits included HIV testing in 2018 and that HIV testing rates varied by race, age group, and region.

Joseph Alvarnas, MD, vice president of government affairs at City of Hope and chief clinical adviser of AccessHope in Duarte, California, spoke March 4 at the closing session of the Association for Community Cancer Centers (ACCC) Annual Meeting & Cancer Business Summit in Washington, DC.

Other gastrointestinal disorders and inflammatory diseases have also been linked to psychiatric disorders, but not much is known about the connection to eosinophilic esophagitis (EoE).

Researchers found that implementing an incremental schedule for hemodialysis in patients with residual kidney disease produced similar clinical outcomes and significant savings for health systems compared with hemodialysis administered on a more traditional schedule.

The association between higher disease activity risk of cardiovascular (CV) events was strongest during the first 6 months of follow-up, the study found.

Debra Patt, MD, PhD, MBA, executive vice president of Texas Oncology, addresses considerations for getting a second COVID-19 booster, or a fourth dose, among survivors of breast cancer or patients currently undergoing treatment as well as those who may be immunocompromised.

The study used rats with monocrotaline (MCT)-induced PAH to examine whether adding dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, would offer any add-on benefit when used with sildenafil.