Jared is a freelance writer for The American Journal of Managed Care® (AJMC®), and previously worked as a senior editor for HCPLive® at MJH Life Sciences®.
He has an MA from University of Sioux Falls. You can connect with Jared on LinkedIn.
Novel Blood Test Could Transform Multiple Myeloma Diagnosis, Monitoring
Investigators believe the SWIFT-seq system holds potential to replace more invasive bone marrow biopsies.
Monocyte-to-Lymphocyte Ratio Linked With Functional Status in CLL
Patients with chronic lymphocytic leukemia (CLL) had significantly lower monocyte-to-lymphocyte ratio values compared with healthy controls.
Alopecia Linked With Increased Cardiovascular Disease Risk
Patients with alopecia universalis and alopecia totalis are at a particularly high risk of cardiovascular disease, a new study has found.
Nonthrombotic Cardiovascular Conditions Also a Concern in MPNs
Patients with myeloproliferative neoplasms (MPNs) appear to be at a higher risk of heart failure and pulmonary hypertension, though more research into the links is needed.
Telomere Length a Promising Avenue in ILD Research
Telomere length can be used in the diagnosis of interstitial lung diseases like idiopathic pulmonary fibrosis, but it likely also has therapeutic implications, according to a new report.
Predictive Model Forecasts Advanced NSCLC Outcomes
The newly developed model has an area under the curve of 0.807 for predicting progression-free survival.
Study Identifies SSc, SLE Gene Expression Signatures
Both systemic sclerosis and systemic lupus erythematosus have down-regulated RGS5, but they also have distinctive genetic expression profiles.
Model Based on EHR Parameters Can Predict 5-Year Multiple Myeloma Risk
Early identification of multiple myeloma could help clinicians intervene more swiftly.
Retinal Images Fuel Noninvasive CKD Detection Model
The use of retinal images can help investigators noninvasively identify chronic kidney disease and assess patient prognosis.
Study of IPF, Cardiovascular Disease Suggests Complex Interplay
Patients with idiopathic pulmonary fibrosis are at a higher risk of certain cardiovascular diseases.
QRISK3 Tool Predicts Thrombotic Events in ET, PV
The QRISK3 assessment is designed for the general population, but it appears to also have utility in patients with essential thrombosis and polycythemia vera.
New Pirtobrutinib Data Compare Favorably With Ibrutinib in CLL/SLL
Pirtobrutinib had a nominally superior overall response rate compared to ibrutinib in certain patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Upadacitinib Shows Strong Efficacy in Phase 3 Alopecia Areata Trial
The trial is one of 2 phase 3 studies of upadacitinib in patients with severe alopecia areata.
PET/CT Helps Predict Relapse in Patients With Myeloma Undergoing CAR T-Cell Therapy
Patients with extramedullary disease had inferior progression-free survival.
New Strategies and Combinations Could Help Address AA Relapse
Janus kinase inhibitors can be paired with corticosteroids or used as monotherapy in the treatment of alopecia areata.
Upfront HSCT More Cost-Effective for Patients With AML in Remission
Proceeding with hematopoietic stem cell transplantation (HSCT) is more cost-effective than delaying the procedure in patients with intermediate-risk acute myeloid leukemia (AML).
TACE Plus SBRT Effective in Large Tumors Caused by HCC
TACE combined with SBRT enhanced survival rates in patients with large hepatocellular carcinoma tumors, offering promising treatment insights.
Brain Radiotherapy Plus ICIs Boost Survival in SCLC With Brain Metastases
A retrospective analysis found whole brain radiation therapy alongside immune checkpoint inhibitors led to “brilliant” 2-year overall survival rates.
AIM-30 Score Predicts Mortality Following Acute Exacerbation of IPF
Factors such as age, smoking status, and body mass index can help clinicians predict a patient’s risk of 30-day mortality.
Number of Medications a Strong Prognostic Indicator in Lymphoma, CLL, MM
Investigators found certain classes of prescriptions were also associated with outcomes, though they do not believe the association is necessarily a causal one.
TP53 Mutations Remain Important Research Focus in Cancer
TP53 mutations can have a significant impact on the prognosis of diseases like chronic lymphocytic leukemia, but their effect can vary based on numerous factors.
Midkine May Play Key Role in SCLC
New data show midkine expression is heightened in small cell lung cancer, suggesting the growth factor may be an important therapeutic target.
Immune Cell Phenotypes Linked With Hypothyroidism, IPF
Thirty-six immune cell phenotypes were flagged as having an association with idiopathic pulmonary fibrosis (IPF).
Venetoclax Consolidation a Feasible Strategy After BTKi in CLL
Switching to venetoclax led to sustained high rates of undetectable minimal residual disease, the investigators found.
Links Between Alopecia and Mental Health Vary by Country
The research showed that certain females—but not males—were at a higher risk of anxiety and depression.
Analysis Highlights Comparative Efficacy of Alopecia Areata Drugs
Investigators found that Janus kinase inhibitors were effective in a dose-dependent manner.
Metabolites With Potential Role in IPF Identified by Genome-Wide Association Study
Of 14 metabolites identified, 2 appeared to have “robust” causal relationships with idiopathic pulmonary fibrosis.
Itepekimab Shows Mixed Results in Phase 3 COPD Trials
Cachexia Worsens Prognosis in Older Patients With Advanced SCLC
Older patients with small cell lung cancer and significant weight loss were more likely to experience dose interruptions than patients with cachexia.
Depemokimab Reduces Exacerbations Regardless of Baseline Asthma Control
Depemokimab significantly reduces asthma exacerbations, benefiting patients regardless of their baseline asthma control levels. A biologics license application for depemokimab is currently being reviewed by the FDA.