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Decorin, a highly conserved, class 1 small leucine-rich repeat proteoglycan expressed in the extracellular matrix, may have a protective effect in a subset of patients with multiple myeloma, investigators concluded.

On this episode of Managed Care Cast, we speak with Tim Gronniger, the CEO of Caravan Health, about what to look for as accountable care organizations (ACOs) and policy makers try to encourage more providers to join value-based care arrangements.

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) who have comorbidities were more likely than those without co-occuring conditions to require revision endoscopic sinus surgery over a 10-year period.

An analysis of 2019 claims data for California Medicaid enrollees shows large disparities in HIV pre-exposure prophylaxis (PrEP) uptake, especially among Black individuals.

For the second straight month, national telehealth utilization, measured as a percentage of all medical claim lines, grew in December 2021, according to FAIR Health’s Monthly Telehealth Regional Tracker.

Data from 2015 show approximately half of US-born adults were exposed to harmful levels of lead as children; Florida’s Department of Health to advise against COVID-19 vaccination for "healthy" children; Black patients remain underrepresented in clinical trials for newly approved drugs despite FDA efforts.

Polypharmacy was associated with a nearly doubled increase in health care expenditures and a tripled increase in pharmacy expenditures among older patients with cardiovascular diseases (CVD).

For 30 days, migraineurs were randomized to an FDA-approved dental device to help jaw clenching or a placebo device.

Writing in Journal of Internal Medicine, researchers examine potential barriers inhibiting uptake of low-dose CT lung cancer screening in Europe.

Japanese patients with psoriasis reported improved objective symptoms and satisfaction with brodalumab.

Jill Hutt, vice president of member services at the Greater Philadelphia Business Coalition on Health (GPBCH), discusses different ways employers motivate employees to partake in the Diabetes Prevention Program (DPP).

A new review article outlines the latest research and results into programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) inhibitors for the treatment of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).

A significant increase has been observed in Texas residents traveling out of state for abortion care; nearly a third of people who previously had COVID-19 cited lingering symptoms up to 1 year after infection; muscle strengthening exercises linked with lower risk of disease and early mortality.

Steven Yeh, MD, professor of ophthalmology at the Truhlsen Eye Institute at the University of Nebraska Medical Center, explains the delivery mechanism and benefits of Xipere for macular edema.

Although chimeric antigen receptor (CAR) T-cell treatments have shown efficacy in certain cancers, targeting multiple antigens and overcoming production limitations may advance the field and make this therapy more effective and accessible.

The cause of the increase is 2-fold: an increased push for personal hygiene practices and the use of personal protective equipment for health care workers.

The QRISK3 model outperformed more traditional models like the Framingham Risk Score, according to a new report.

A recent review concluded that polysomnography tests have objective value in assessing the effect that socioeconomic status has on sleep quality.

Natalie Dickson, MD, president and chief strategy officer of Tennessee Oncology, discusses Tennessee Oncology's role in the discussion to reform 340B.

A lack of transparency and misaligned incentives had curtailed the adoption of biosimilars in the United States.

Parkinson disease is believed to have a prodromal phase, long before neuronal death occurs, and some studies have focused on the gut-brain axis to look for clues.

Although asthma disproportionately affects Blacks and Hispanics in the United States, they are more likely to be dissatisfied with their care teams as well as underrepresented in research, according to abstracts at the 2022 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting.

A new report from the CDC details how services for HIV, sexual health, and viral hepatitis were affected in the aftermath of the COVID-19 pandemic, according to data from 2019 and 2020.

A small study found that decreased retinal vascular density identified by optical coherence tomography angiography may be linked to faster visual field loss at extended follow-up.

According to the study, rheumatoid arthritis (RA)-associated autoimmunity was not linked to increased cardiovascular (CV) event risk, suggesting systemic inflammation is likely required for precipitating CV events.

The researchers observed internal consistence and convergent validity, leading them to suggest the tool be incorporated as a clinical standard in spinal muscular atrophy (SMA) care.

Eosinophilic esophagitis (EoE) has a psychological impact on children and families with the condition, says Colette Romero, who advocates for more awareness of the condition.

In Poland, the prevalence of chronic rhinosinusitis with nasal polyps was shown to be greater in men, elderly individuals, and those living in urban areas.

A session moderated by the president of the Association of Community Cancer Centers (ACCC) examined the business case for having oncology pharmacists and oncology social workers on community cancer care teams.

Low-burden mutations, or minor clones, of TP53 abnormalities were once thought to be of little significance but that is no longer the case, according to a recent report.