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Researchers presented results for ZB131, a monoclonal antibody that would target cancer-specific plectin (CSP); experiments with mice showed this may be present in more than 80% of the most common types of cholangiocarcinoma.

A recent study found that behavioral problems in adolescents with attention deficit/hyperactivity disorder (ADHD) were associated with chronotype, a person’s circadian preference.

Roxana Siles, MD, FAAAAI, staff in the Department of Allergy and Immunology at Cleveland Clinic and codirector of the Asthma Center at Cleveland Clinic, addresses the factors that contribute to necessitating multispecialty management of patients with chronic cough.

The researchers found that the prognostic values for both overall and progression-free survival remained even after adjusting for the International Prognostic Index, a widely used prognostic model of outcomes for the disease.

Camille Hertzka, vice president, head of oncology, US Medical, AstraZeneca, clarifies testing for the HRR mutation in metastatic castrate-resistant prostate cancer (mCRPC) and the predictive importance of radiographic progression-free survival (rPFS) for overall survival in this setting.

Researchers investigated polypharmacy incidence in one of the fastest-aging regions in Spain.

A study conducted in Saudi Arabia found that the severity of dry eye disease (DED) was associated with the amount of quality sleep participants received.

A recent review found that factors influencing blood eosinophil stability, a potential biomarker for chronic obstructive pulmonary disease (COPD), need further research.

Improvements in time spent in target range and glycated hemoglobin A1c were investigated among 34 children with type 1 diabetes (T1D) with a history of daily insulin use and no prior use of diabetes technology.

White House seeks to reduce medical debt of Americans amid rising inflation; Biden administration asks federal appeals court to resume enforcement of a COVID-19 vaccine mandate for federal employees; Philadelphia to reimpose mask mandates in indoor public settings.

In patients with intermediate- to high-risk, use of pegfilgrastim biosimilars could optimize management of FN risk.

Researchers found no association between the use of tofacitinib, tocilizumab, or tumor necrosis factor (TNF) inhibitors and risk of developing Alzheimer disease and related dementia (ADRD) among older patients with rheumatoid arthritis (RA).

Marc-Andre Cornier, MD, professor and director of the Division of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, outlines the necessary components for a successful weight loss program.

Flow–minimal residual disease (MRD) assessment in patients with multiple myeloma (MM) was found to be a good tool for early detection of MRD and could aid providers in treatment decision-making.

Patient-reported treatment goals for psoriasis showed varied preferences according to characteristics such as age, severity, and gender, but the top goal overall was to have confidence in the therapy.

Across 3 disease states, dupilumab has been shown to create rapid, clinically meaningful responses that were sustained, which could improve adherence and the patient-provider relationship.

Black children with systemic lupus erythematosus (SLE) are at the highest risk of adverse renal outcomes, the study found.

On this episode of Managed Care Cast, Perry N. Halkitis, PhD, MS, MPH, dean of the Rutgers School of Public Health, discusses training the next generation of public health professionals.

Findings suggest measuring excess weight in patients may help predict the development of radiation pneumonitis.

Rural hospitals find themselves targets of cyber attacks; a shortage of baby formula follows a nationwide recall; COVID-19 cases likely undercounted.

Stephen Schleicher, MD, MBA, chief medical officer of Tennessee Oncology, talks about lessons learned from the Oncology Care Model (OCM) and Medicare that are being used to innovate toward value-based care.

Kleine-Levin syndrome is rare and difficult to diagnose, especially when symptoms are atypical. Recent research points to LMOD3 variations as a potential diagnostic marker if confirmed by further research.

Analyzing whole-mount histologic large sections is not a new practice, but a new strategy was needed to fully characterize peripheral nerve invasion in hilar cholangiocarcinoma.

Cross-border acquisition of medications such as antibiotics has long been a practice in US communities bordering Mexico, and a lack of sufficient insurance is one driver of the trend, according to a recent study.

Despite underrepresentation in clinical trials of acute coronary syndrome treatments, a recent study suggests treatment strategies and outcomes in chronic kidney disease patients with ST-elevation myocardial infarctions (STEMI) have improved over time.

With further research, allogeneic CAR T-cell therapy may help overcome the cost and production time barriers currently associated with autologous CAR T-cell therapy.

This subanalysis of data from the ECOG-ACRIN E5103 trial evaluated longer-term quality of life (QOL) at the 18-month mark among patients with lymph node–positive or high-risk lymph node–negative breast cancer (BC) who have completed active treatment.

Circulating B cell–activating factor was shown to be a potential biomarker in identifying blood eosinophil counts and risk of postoperative nasal polyp recurrence among patients with chronic rhinosinusitis with nasal polyps (CRSwNP).

A recent study aimed to identify associations between socioeconomic status, allostatic load, and clinical trial end points in patients with multiple myeloma (MM).

Pollutant particles with a smaller diameter, density, and flow rate can enter the deep lung, but large particles with a low density may also enter the deep airways, according to a study.