All News

Prescribing is a complex process with multiple factors to consider on top of the 3 primary questions about effectiveness, harm, and cost. Pharmacogenetics has put this complexity under the spotlight and prompted educational programs and the development of new clinical decision support systems.

Whole-exome sequencing of a family with early-onset cancers found a novel variant in programmed cell death 1 ligand 2 that could potentially indicate germline predisposition to lymphoma.

The FDA approval for Fylnetra represents the fifth approval for a biosimilar referencing Neulasta (pegfilgrastim) in the United States.

Risk of ectopic pregnancy, the leading cause of maternal morbidity and mortality in the first trimester of pregnancy, was significantly associated with psoriasis in Danish women, especially those with moderate to severe disease.

For the second year, the meeting will focus on health equity, as American Society of Clinical Oncology (ASCO) President Everett Vokes, MD, FASCO, has selected the theme “Advancing Equitable Cancer Care Through Innovation.”

Regeneron will purchase Sanofi’s stake of cemiplimab (Libtayo) for $900 million in addition to royalties and other possible payments; a patient receives a 3D printed ear implant created using her own cells; the FDA accepts Pfizer’s EUA application for its COVID-19 vaccine for children aged younger than 5.

A cure for sickle cell disease could more than double the lifetime incomes of patients, the study found.

Randall A. Oyer, MD, medical director, oncology, and medical director, Cancer Risk Evaluation Program, Lancaster General Health, and clinical professor of cancer biology at Penn Medicine, discusses the recent American Society of Clinical Oncology/Association of Community Cancer Centers recommendations for improving diversity in clinical trials.

Forty-two percent of patients in the cohort had an adverse pregnancy outcome.

Kashyap Patel, MD, CEO of Carolina Blood and Cancer Care Associates, current president of the Community Oncology Alliance, and associate editor of Evidence-Based Oncology™, talks with us ahead of the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.

Susan Redline, MD, MPH, professor of sleep medicine and epidemiology, Harvard T.H. Chan School of Public Health, gives a preview of her SLEEP 2022 keynote and discusses her 30 years of sleep epidemiology advocacy.

Encouraging outcomes in recent studies have the authors of a recent review calling for more research on the effect of cannabinoids on sleep disorders.

Body mass index did not appear to correlate with glycemic control, the study found.

HHS announces Office of Environmental Justice; CDC says Memorial Day weekend COVID-19 cases were up nearly 6 times over last year; World Health Organization says the monkeypox outbreak is unlikely to lead to a pandemic.

Research presented at EULAR 2022 demonstrated the pharmacokinetic equivalence of a low-concentration version of the adalimumab biosimilar SB5 and a high-concentration version.

From discussions on policies of time change to the neurobiology of narcolepsy, sessions at the SLEEP 2022 conference taking place June 4-8 will span a broad range of topics.

Research supports that aquatic exercise is effective at reducing pain and disease activity and improving physical function, although it is unclear whether it is more effective than any other form of therapy for inflammatory arthritis (IA).

A population-based cohort study found that patients with chronic kidney disease (CKD) or who underwent a recent kidney transplant had a higher risk of cancer compared with people with normal kidney function.

Pediatric patients with early-onset atopic dermatitis (AD) who reported incidence of food sensitization were associated with later allergic respiratory diseases, in which persistence of AD was linked with multiple food allergies.

A systematic review found that vision impairment was associated with greater symptoms of depression and anxiety in children.

A recent review points to a host of potentially disease-modifying agents currently in clinical trials.

Results of a cross-sectional study revealed wide disparities in emergency department (ED) use among patients with diabetes between 2008 and 2017.

A cohort study found that male and female patients with chronic obstructive pulmonary disease (COPD) had different comorbidities that predicted their risk of mortality.

This new study, from Taiwan, investigated how menopause affects ventricular structure and function and its possible impact on heart failure among women.

Tisagenlecleucel (tisa-cel) was approved to treat adults with relapsed or refractory (R/R) follicular lymphoma. This is the third indication for the therapy since it became the first FDA-approved chimeric antigen receptor T-cell therapy in 2017.

US adult outpatients with psoriasis have a greater risk of developing nonalcoholic fatty liver disease compared with those without the skin condition.

It is still unknown whether the relationship between polypharmacy and malnutrition is bidirectional and authors could not determine causation.

Will Nutland, DrPH, is cofounder of PrEPster, honorary assistant professor at the London School of Hygiene and Tropical Medicine, and an activist.

This new study from Canada compared outcomes in patients living with type 1 diabetes who used 2 closed-loop insulin delivery systems: a fully artificial pancreas that did not require meal input and a hybrid artificial pancreas that required carbohydrate counting.

Medicare recipients will see a reduction in premium costs in 2023, although the amount has not yet been announced; the FDA is investigating a hepatitis A outbreak potentially linked to organic strawberries sold by FreshKampo and HEB; approximately 20,640 American adults will be diagnosed with esophageal cancer in 2022, data suggest.