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The authors found that the relationship between immunosuppressive cells and effector T cells in hilar and distal cholangiocarcinoma has important implications for treatment, in that the tumor microenvironment would likely need to be primed for a treatment strategy to be effective.

A large systematic review on pregnant women living with HIV found that protease inhibitor–based antiretroviral therapy (ART) use was associated with increased risk of babies being born small or very small for their gestational age, but not with other adverse pregnancy outcomes.

A recent study found a correlation in patients with an IgE-mediated food allergy (IgE-FA) reporting symptoms of eosinophilic esophagitis (EoE), leading researchers to conclude screening for EoE may be beneficial.

Age at symptom presentation was significantly associated with longer symptom duration for children with juvenile idiopathic arthritis (JIA).

Dennis P. Scanlon, PhD, professor of health policy and administration at Pennsylvania State University and editor-in-chief of The American Journal of Accountable Care®, talks about major systemic and fundamental barriers to health systems becoming learning health systems.

Although the widespread use of low dose computed tomography screening for lung cancer has led to improved mortality in recent years, disparities in uptake persist throughout the United States.

President Joe Biden announced plans to increase research on long COVID-19; the Oklahoma House voted 70-14 in favor of a near-total abortion ban; Walgreens is going to trial in Florida’s opioid epidemic lawsuit.

Marc-Andre Cornier, MD, professor and director of the Division of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, explains recent research on a behavioral weight loss intervention.

Why persons with type 1 diabetes and continuous insulin infusion fail to achieve optimal glycemic control was the subject of a recent focus group analysis conducted among 37 adult men and women.

A recent study found that nocturnal nasal congestion in patients with hypertension and comorbid obstructive sleep apnea (OSA) was associated with uncontrolled blood pressure (BP).

Patients with atopic dermatitis who achieved rapid changes in skin pain severity with the Janus kinase inhibitor baricitinib were associated with clinically significant improvement in Dermatology Life Quality Index scores.

Panic disorders and specific phobias were the mental disorders most often seen among individuals who have chronic thromboembolic pulmonary hypertension (CTEPH), according to new research.

Complications were significantly associated with low height, high-dose prednisolone use, and progression of cervical spine lesions in early disease stages of rheumatoid arthritis (RA).

In this case, a patient died 18 months following his transplant after developing de novo intrahepatic cholangiocarcinoma.

A recent study found that retinal age gap, defined as chronological age subtracted from retinal age, is a potential indicator of Parkinson disease development.

The Biden administration plans to expand Affordable Care Act (ACA) coverage to more families; new guidelines jointly announced by cardiology organizations for the treatment and prevention of heart failure; World Health Organization estimates that 99% of people worldwide are exposed to poor air quality.

A small study conducted in Melbourne, Australia, found that older age and being from a culturally and linguistically diverse community were associated with less awareness of pulmonary rehabilitation among patients with chronic obstructive pulmonary disease (COPD).

Mitigating the high cost of prescription drugs is a win-win to address the complex, multipronged problem of getting patients to take their medications as advised.

Two abstracts presented at the 2022 American Academy of Dermatology (AAD) Annual Meeting explored the health-related quality of life (QOL) and mental health impact of psoriasis disease burden by severity and affected body region.

With more people living with HIV now reaching advanced ages and qualifying for Medicare coverage, this new study investigated HIV-related influences on their health care spending, particularly antiretroviral therapy (ART), compared with a population who does not have HIV.

New research published in Health Affairs details the rates of specialty medication noninitiation among Medicare Part D beneficiaries.

Patients hospitalized for acute heart failure and prescribed empagliflozin saw improvements in quality of life at 15 and 90 days post-discharge. The study may make the case for prescribing SGLT2 inhibitors before patients leave the hospital.

Researchers presented new data on patient characteristics and outcomes seen in the VICTORIA trial of vericiguat.

Norman E. “Ned” Sharpless, MD, is departing shortly after the launch of Cancer Moonshot 2.0, an initiative that aims to reduce the cancer death rate by at least half over the next 25 years while improving the experience for all those affected by cancer.

Melissa Johnson, MD, program director of Lung Cancer Research at Sarah Cannon, discusses the need for increased lung cancer screening among patients who have no tobacco use history.

Later school start times are being considered to address youth mental health crises; states are taking action to enact legislation on opioid addiction and fentanyl-related deaths; Unilever recalls 2 Suave aerosol antiperspirant products due to a potential carcinogen.

A review expanded on urological complications associated with Parkinson disease (PD), as well as therapies for these complications.

Immune checkpoint inhibitors have changed the treatment landscape of certain cancer types, and a recent study aims to provide new insight on why treatment response varies so much from patient to patient.

Debra Patt, MD, PhD, MBA, executive vice president of Texas Oncology, explains recommendations for annual mammography screenings after COVID-19 vaccination and why guidelines differ for diagnostic visits.