Mitochondrial Stabilizing Drugs Have Potential to Reverse Vision Loss in Dry AMD
February 10th 2023A review of data on 2 mitochondrial membrane stabilizers—risuteganib and elamipretide—has highlighted the potential to not just slow disease progression but actually reverse vision loss in patients with intermediate dry age-related macular degeneration (AMD).
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CMS Releases Guidance on the Math Behind Part B, Part D Drug Rebates
February 10th 2023The Biden administration released 2 sets of guidance documents for pharmaceutical manufacturers about how it plans to implement the new Medicare Prescription Drug Inflation Rebate Program as required under the Inflation Reduction Act, and said some beneficiaries could see lower coinsurance for some Part B drugs as soon as April 1.
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Dr Kirk Campbell Discusses Mount Sinai’s Educational Research, Clinical Initiatives on Health Equity
February 9th 2023Kirk Campbell, MD, FASN, Vice Chair for Diversity, Equity, and Inclusion in the Department of Medicine at Mount Sinai Health System in New York, spoke on educational initiatives implemented by Mount Sinai to train resident physicians, medical students, and senior faculty on health equity, as well as further research efforts to address disparities.
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Adult Immunization Recommendations Receive Update for 2023
February 9th 2023The Advisory Committee on Immunization Practices released the update to the Recommended Adult Immunization Schedule for all US residents aged 19 years and older, which has been approved by the CDC and medical groups.
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Brexucabtagene Autoleucel Shows High Rate of Durable Response at 3 Years
February 9th 2023Chimeric antigen receptor T-cell therapy brexucabtagene autoleucel showed a rate of complete remission of 71% and a rate of complete remission with incomplete hematologic recovery of 56%, according to 3-year follow-up results.
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Jessica Allegretti, MD, MPH, medical director of the Crohn's and Colitis Center, Brigham and Women's Hospital, discussed how the FDA’s approval of Rebyota for the prevention of recurrent Clostridioides difficile infection (CDI) may promote cost effective management of CDI for patients and health systems.
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While treatment with allogeneic hematopoietic cell transplantation (allo-HCT) showed improved disease-free survival compared with conventional consolidation chemotherapy, the findings suggest there may not be an overall survival (OS) benefit with allo-HCT for patients with intermediate-risk acute myeloid leukemia (AML) during first complete remission.
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Hyaluronic Acid Spacer May Reduce Rectal Dosimetry, GI Toxicity From Prostate Cancer Treatment
February 9th 2023A randomized controlled trial found that the use of a rectal spacer may help mitigate the gastrointestinal (GI) toxicity associated with hypofractionated radiation therapy for prostate cancer.
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China’s angry reaction after spy balloon retrieval rouses drug supply chain anxiety; after allegedly overcharging California’s Medi-Cal program, managed care company Centene will pay millions in a settlement; major drug companies are chasing new pharma deals amidst dropping patent exclusivity.
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Dr Michael Cohen Discusses Accessibility of Future Gene Therapies
February 9th 2023Michael N. Cohen, MD, FAAO, retinal surgeon at Wills Eye Hospital in Philadephia and Mid Atlantic Retina, speaks about the future of gene therapy and the accessibility and availability of these therapies moving forward.
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Use of Population-Based Risk Score Might Fail to Detect Frailty in Hospitalized Patients With COPD
February 8th 2023A study of patients hospitalized for chronic obstructive pulmonary disease (COPD) exacerbation found that exclusively using the population-based Hospital Frailty Risk Score tool to assess for frailty may cause it to go undetected and untreated.
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Angiogenesis Meeting to Highlight Latest in Technology, Translational Research, Clinical Trials
February 8th 2023The Angiogenesis, Exudation, and Degeneration 2023 meeting will be held virtually with a program focused on understanding and treating neovascular, exudative, and degenerative diseases of the eye.
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Biden’s State of the Union (SOTU) address emphasized drug access for those on Medicare, the Cancer Moonshot, and more; HIV diagnoses are increasing in Washington, DC, from missed wellness visits and preventive visits upended during the start of COVID-19; California online women’s pharmacy The Pill Club will pay $18.3 million in Medicaid fraud settlement with California.
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Bloodstream Infection Risk Associated With Race, SES Among Patients on Hemodialysis
February 7th 2023Data released in the CDC’s latest Morbidity and Mortality Weekly Report indicate that patients with end-stage kidney disease on hemodialysis who are Black, Hispanic/Latino, or of lower socioeconomic status (SES) are at greater risk of Staphylococcus aureus bloodstream infections, with Hispanic/Latino ethnicity cited as an independent risk factor.
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Intermountain Healthcare and Story Health Partner to Optimize Rural Heart Failure Care
February 7th 2023On this episode of Managed Care Cast, we speak with Tom Stanis, CEO and cofounder of Story Health, and Phillip Wood, Intermountain Ventures program director, on how their partnership came about, how it is going so far, and the future of their collaboration.
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CVS Health Corp. is nearing a $10.5 billion deal to take on Oak Street Health Inc.; an innovative cystic fibrosis drug that can lengthen life expectancy for patients is blocked by high costs and unavailability in low-income countries; New York City will end the COVID-19 vaccine mandate for city workers.
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