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Abstracts presented at Digestive Disease Week 2022 showed that RBX2660, an investigational microbiota-based drug, was more likely to reduce the recurrence of Clostridioides difficile infection (CDI) compared with placebo.

If there's one silver-lining of the COVID-19 pandemic, it is the opportunity to talk openly about mental health issues.

The logistics for storing chimeric antigen receptor (CAR) T-cell therapies remain a challenge, said Joel Wayment, vice president of operations for 3PL Services, Cardinal Health.

The authors of this study evaluated outcomes among children aged 7 to 16 years, all living with type 1 diabetes (T1D), who attended a 3-day virtual education camp that focused on their use of a closed-loop control (CLC) system for insulin delivery.

United States birth rate rises from last year but is still lower than pre-pandemic; a drug plant closure in California could affect availability of 5 essential medications; the No Surprises Act prevented 2 million potential surprise bills in first 2 months of 2022, report says.

At Digestive Disease Week 2022, John M. DeWitt, MD, professor of medicine, Indiana University Health, explains his findings on the diagnosis and management of achalasia in 2022 and how the COVID-19 pandemic affected these trends.

During a State-of-the-Art Lecture at Digestive Disease Week 2022, Jessica L. Mellinger, MD, MSc, explained how the COVID-19 pandemic has driven increases in rates of alcohol use and associated liver disease, as well as what can be done at the clinic, societal, and policy levels to address these trends.

At Digestive Disease Week 2022, Sravanthi Parasa, MD, gastroenterologist at Swedish Gastroenterology, talks about how artificial intelligence (AI) is used in gastroenterology and what challenges it may pose for clinicians.

A study conducted in China found that cybervictimization was associated with sleep problems, anxiety symptoms, and depressive symptoms in adolescents.

Patients of Asian heritage were also more likely to have end-organ manifestation, the authors found.

While the burden on caregivers of family members with neurodegenerative diseases such as Parkinson disease (PD) is well known, data on longitudinal trajectories of this burden are limited; this study followed caregivers for 2 years.

A recent study found that patients with chronic kidney disease (CKD) had a poor prognosis based on glomerular filtration rate (GFR), ankle-brachial index (ABI), and high systolic blood pressure in a 16-week exercise program.

New findings from a prospective cohort study outline associations between diabetes medications and common eye conditions, such as open-angle glaucoma and age-related macular degeneration (AMD).

Medical oncologist Jeffrey S. Weber, MD, PhD, spoke with The American Journal of Managed Care® (AJMC®) about how treatment options have improved for more advanced melanoma cases and the role that genetic mutations play in choosing therapy.

Investigational microbiota-based live therapeutic RBX2660 was found to be safe and effective at reducing Clostridioides difficile (C difficile) recurrence, said Paul Feuerstadt, MD, assistant clinical professor at Yale University School of Medicine, gastroenterologist at PACT Gastroenterology Center, at Digestive Disease Week 2022.

The dysfunction with pharmacy benefit managers (PBMs) is so troublesome that the Federal Trade Commission (FTC) is currently investigating how they have driven up costs. Until May 25, the FTC is holding a public comment period on PBM practices.

Pfizer announced positive data of its COVID-19 shot regimen for children under 5 years; providers gear up for increased challenges in distributing abortion medication; hypoallergenic baby formula shipments arrive in the United States.

Evidence shows that weight loss achieved through bariatric and endoscopic surgery can help treat and reverse nonalcoholic fatty liver disease (NAFLD), but optimal procedure selection and timing vary by patient factors, according to speakers at Digestive Disease Week 2022.

Outcomes were worse for patients hospitalized once for Clostridioides difficile infection compared with alternative reasons for hospitalization, but the risk of adverse outcomes did not seem to increase with recurrent admissions for C difficile, explained Preethi Venkat, MD, second-year internal medicine resident at University of California, San Diego, at Digestive Disease Week 2022.

A pair of posters presented at Digestive Disease Week 2022 showed the efficacy of an investigational biotherapeutic in preventing Clostridioides difficile infection recurrence and restoring the microbiome.

A recent study identified TIGIT as a marker of chimeric antigen receptor (CAR) T-cell exhaustion and found it to improve CAR T-cell therapy efficacy in preclinical models.

Dupilumab was associated with reductions in exacerbations and oral corticosteroids (OCS) dosage, as well as improved lung function, in patients with OCS-dependent asthma with and without comorbid chronic rhinosinusitis with nasal polyps.

Roxana Siles, MD, FAAAAI, staff in the Department of Allergy and Immunology at Cleveland Clinic and codirector of the Asthma Center at Cleveland Clinic, discusses the important need for chronic cough therapies and what issues with current treatments should be addressed by next-generation medications.

Speakers at Digestive Disease Week 2022 presented research on how health disparities and socioeconomic factors can contribute to changes in the gut microbiome that have implications for cancer risk, immune health, and overall well-being.

Because symptoms are similar to those of gastroesophageal reflux disease, achalasia is often misdiagnosed, explained Eric Low, MD, MPH, gastroenterology fellow at University of California, San Diego at Digestive Disease Week 2022.

The tools we need to achieve long-term stability for community providers and ensure better outcomes for rural Americans are available, and CMS can help us utilize them.

The microenvironment of the skin also helps explain why certain ethnicities appear to have a higher risk of melanoma.

The accumulation of screening and treatment disparities are contributing to colorectal cancer incidence and mortality disparities, said Folasade (Fola) May, MD, PhD, gastroenterologist, health services researcher at University of California, Los Angeles, at Digestive Disease Week 2022.

As artificial intelligence (AI) technology in the gastrointestinal field continues to advance, speakers at Digestive Disease Week 2022 discussed how these tools can be put into practice to improve efficiency, reduce physician burnout, and reap cost savings.

Differentiation between multiple myeloma (MM) and bone metastases from other cancers can be difficult, but radiomics-based models have potential to improve diagnostic accuracy.