All News

Surveys of health care professionals, patients, and caregivers explored unmet needs in sickle cell disease (SCD), as well as the significant impact the disease has on everyday life.

Major adverse cardiac events are rare but serious in patients treated with immune checkpoint inhibitors (ICIs), and increased awareness is crucial to identify and treat these conditions in a timely manner.

Recommendations discuss appropriate use and diagnostic, prognostic, and therapeutic implications of cardiac genetic testing, including guidance on impact of exercise.

High-intensity interval training (HIIT) also improved quality of life and physical activity levels while reducing anxiety and depression levels.

A digital health intervention delivered via smartphone showed that current anxiety symptoms predicted both current and later depressive symptoms.

The FDA authorized COVID-19 vaccine for children under 5 years; more than 400,000 over-the-counter (OTC) medications were recalled; medication imports from Canada and the United Kingdom see bipartisan approval in the Senate.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Researchers found significantly higher incidence rates of of type 2 diabetes (T2D) in children with nonalcoholic fatty liver disease compared with other groups.

Despite the increased prevalence of insulin pump use over the past 2 decades, there have been few improvements in uptake of the devices among patients who are Black or who come from lower socioeconomic levels.

The primary outcomes of this secondary analysis of the MOTIVATE-HF study were improvement in caregiver self-efficacy while caring for patients living with heart failure and caregiver contributions to self-care for these patients following motivational interviewing.

Elaine Siegfried, MD, professor of pediatrics and dermatology, Saint Louis University Health Sciences Center, discusses therapeutic management considerations for dermatologists in consulting with diverse patients with atopic dermatitis.

Levels of the hormone increase with disease severity, a new study has found.

According to the researchers of the study, managing patients with hidradenitis suppurativa holistically may help reduce the burden of their disease.

Incidence of chronic rhinosinusitis (CRS) was associated with a higher rate of current and past proton pump inhibitor (PPI) use, in which elevated risk of PPI use and prescription duration were only found in those with CRS who did not have nasal polyps.

About 3 times as many of the children and teenagers taking dulaglutide had a glycated hemoglobin level of less than 7.0% at 26 weeks compared with those on placebo.

Tracking tool Meta Pixel was found on 33 of the top 100 US hospitals’ websites; the Environmental Protection Agency (EPA) released new guidance in response to dangerous PFAS levels in drinking water; the US abortion rate rose by 7% between 2017 and 2020.

As part of the Biosimilars Initiative, British Columbia, Canada, implemented a mandatory switch to biosimilar insulin glargine for patients covered by the province’s drug plan.

Increased diversity in clinical trials remains an unmet need, and in the new SEQUOIA trial, the majority of patients being White males meant researchers could not do a subgroup analysis looking at outcomes for specific races, age groups or genders, said Mazyar Shadman, MD, MPH, of Fred Hutchinson Cancer Research Center.

The study, based on a case series in Japan, found the risk of grade 2 or above chemoradiation increased when durvalumab was started within 14 days of the final thoracic radiotherapy treatment.

Hope S. Rugo, MD, FASCO, is professor of medicine and the director of the Breast Oncology and Clinical Trials Education program at the University of California San Francisco Helen Diller Family Comprehensive Cancer Center. She discusses her experience with palbociclib and letrozole in advanced breast cancer.

Omid A. Hamid, MD, chief of Translational Research and Immunotherapy, director, Melanoma Therapeutics, The Angeles Clinic and Research Institute, spoke with The American Journal of Managed Care® (AJMC®) about evaluating therapy options for patients with advanced melanoma.

A literature review revealed that supplementation with vitamin D could provide therapeutic benefits for patients with multiple myeloma (MM) who are undergoing chemotherapy. However, more research is needed to confirm findings.

The new trial was the first to investigate outcomes among a patient population living with HIV (PLWH) who were treated for anal precancerous growths, or high-grade squamous intraepithelial lesions.

A rare genetic variation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) is significantly association with an increased risk of cataracts.

Immune checkpoint inhibitors have changed the way certain cancers are treated, but more can be done to optimize treatment and improve patient responses.

Investigators said the benefits appeared relatively early in treatment for many patients and persisted throughout the study period.

Sex and age were associated with clinical characteristics of geriatric psoriasis, including type and location of disease, therapeutic considerations, and risk of comorbid nail involvement and psoriatic arthritis.

The Supreme Court has ruled that HHS' decision to lower reimbursement rates to hospitals so that those in the 340B program received reduced rates because they received discounted drugs was unlawful.

FDA advisers unanimously recommend approval for Moderna’s COVID-19 vaccine for children aged 6 to 17 years; new guidelines lower the recommended minimum age for starting gender transitioning treatments; the World Health Organization (WHO) will decide next week whether monkeypox is a global public health emergency.

A single-center analysis of more than 30 years of data shows rates of preterm births and preeclampsia remained stable