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Targeting everyday chronic conditions to rare diseases that require costly, sometimes 1-time treatments, CMS Tuesday announced an intent to test 3 new models in an effort to lower drug prices and widen access to expensive, life-changing therapies for patients in Medicare and Medicaid.

Data showed that 64% of adults without any type of diabetes had overweight or obesity, compared with 62% of adults with type 1 diabetes (T1D) and 86% with type 2 diabetes between 2016 and 2021.

The phase 3 PhALLCON study found ponatinib plus chemotherapy more effective than imatinib with chemotherapy in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.

Early initiation of prophylaxis regimens and joint status monitoring over time are the most relevant aspects of evaluating treatment efficacy in this patient population, study authors concluded.

Children with epilepsy had an increased risk for injuries requiring hospitalization compared with controls in Finland, with boys showing greater risk than girls among all included participants.

Amy Crawford-Faucher, MD, vice chair of the Primary Care Institute and Department of Family Medicine at Allegheny Health Network, discussed recent reports from the World Health Organization about COVID-19.

Evidence suggests as many as 29% of people with myeloproliferative neoplasms (MPN) or myelodysplastic syndrome (MDS)/MPN have chronic kidney disease.

HHS wants to require nursing homes to disclose more ownership and management information; privacy advocates warn that mental health data can legally be sold from certain platforms not covered by the Health Insurance Portability and Accountability Act; the FDA won’t review Soligenix’s cancer drug proposal because of an insufficient application.

The CAPTURE screening tool showed high specificity but low sensitivity in identifying primary care patients with previously undiagnosed chronic obstructive pulmonary disease (COPD).

The US Preventive Services Task Force (USPSTF) reaffirmed previous recommendations against routine serologic screening for genital herpes infection among asymptomatic adolescents and adults, including pregnant individuals.

A nightly use of 0.05% atropine eyedrops resulted in a lower incidence of myopia compared with placebo.

The study found 143 loci where somatic copy numbers were varied based on genetic ancestry.

Implications of these findings include a more clear understanding of the burden imposed by heart failure (HF), which encompasses the cost of care and adverse health outcomes.

A new study found that protection from the Omicron variant waned 6 months after the second dose of a COVID-19 vaccine in older patients.

Data show that patients who have factor VIII (FVIII) inhibitor titers of 20 or higher BU/mL took longer to achieve complete responses (CR) and had lower CR rates vs patients with lower titers.

This agreement enables the integration of data from Dexcom’s continuous glucose monitor (CGM) directly into DarioHealth's metabolic digital health tool, adding another layer of support.

Congress has no solution for out-of-network ambulance rides; teenagers going to an emergency department in a mental health crisis don't receive necessary follow-up care; Medicaid explores nutritional benefits of food as medicine spending in some states.

Overall survival and recurrence-free survival showed substantial improvement when physicians more closely followed quality recommendations for non–small cell lung cancer (NSCLC).

While the current therapies are effective for treating branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO), they are inadequate for long-term treatment in clinical practice, according to an analysis of real-world data.

Two studies looking at a higher dose of aflibercept found that an 8-mg dose can be maintained at longer dosing intervals with similar benefits and no additional safety signals compared with the 2-mg dose.

Mary Cushman, MD, professor of medicine at the University of Vermont, and director of the thrombosis and hemostasis program at the University of Vermont Medical Center, talks about racial disparities in pulmonary embolism treatment.

Whitney Jones, MD, chief medical advisor at GRAIL Inc, discusses the PATHFINDER study of multi-cancer early detection testing.

Individuals exposed to antidepressant drugs for longer than 365 days had an increased risk of epilepsy, particularly those given escitalopram, venlafaxine, and mirtazapine, according to a recent study conducted in Taiwan.

This exploration of eczema self-management investigated the potential effectiveness of 2 online behavioral interventions, 1 each for young patients and their parents and/or caregivers.

Interventions in 9 studies were linked with varying effects on glycated hemoglobin, type 1 diabetes (T1D) management adherence, self-management behaviors, and parent-child teamwork in T1D management.

An analysis of 112 infant deaths found that the contribution of genetic diseases to mortality was higher than previously known, and that treatments are available for 30% of the genetic diseases uncovered by the study.

The researchers underscored the importance of their findings for a wide group of patients with inherited bleeding disorders, as most colorectal cancer (CRC) screening programs across the globe use fecal immunochemical testing (FIT).

The subset of patients with psoriatic arthritis had the highest odds ratio of migraine.

Home optical coherence tomography (OCT) has shown there is a wide degree of heterogeneity in fluid dynamics and treatment response that may not be clear during regular office visits and scans. Presenters reviewed the latest data in home OCT to manage wet age-related macular degeneration (AMD).

The patient, an 83-year-old man, experienced onset of myasthenia gravis after a severe SARS-CoV-2 infection.