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Making LDL Matter Again: Addressing Clinical, Patient, and Payer Barriers in ASCVD Management : Episode 13
Adherence and Persistence
Panelists discuss how improving adherence to LDL-lowering therapies is essential for sustained cardiovascular protection.
EP: 1.Understanding the Current State of LDL-C Goal Attainment and Barriers to Adequate Control in Hyperlipidemia
EP: 2.Challenges with Undertreatment in Hyperlipidemia and Opportunities to Address this Gap
EP: 3.Pharmacy-Driven Challenges
EP: 4.Real-World Insights and PROMPT-LIPID
EP: 5.Social Determinants of Health
EP: 6.The 2013 Guideline Shift
EP: 7.Unintended Consequences of Metric Changes
EP: 8.Reinstating LDL-C Targets
EP: 9.International LDL Thresholds
EP: 10.Nonstatin Therapy Decisions
EP: 11.PCSK9 Inhibitor Underuse
EP: 12.Payer and Prior Authorization Barriers
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EP: 13.Adherence and Persistence
EP: 14.Cumulative LDL-C Exposure
EP: 15.Economic Burden and Systemwide Strategies
Panelists discuss how adherence to low-density lipoprotein (LDL)–lowering therapy, particularly injectables, remains one of the greatest challenges to long-term success. Patients often discontinue treatment due to side effects, inconvenience, or lack of follow-up support.
Pharmacists and health systems can play a key role in monitoring persistence, providing reminders, and counseling patients about the benefits of sustained therapy.
Panelists emphasize that simplifying treatment regimens and enhancing digital engagement could improve adherence and outcomes.
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