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Researchers studied data from 5 phase 1 studies that took place between 2012 and 2021, comprising 139 infusions among patients with B-cell acute lymphoblastic leukemia who received chimeric antigen receptor (CAR) T-cell treatment.

The pandemic has changed how care has delivered, but what professionals new to health care know about strategies used to connect with patients in a virtual setting, or the quality of the instruction they receive, is not known.

Katherine R. Tuttle, MD, FASN, FACP, FNKF, a nephrologist from the University of Washington and Providence Health Care, discussed new consensus guidelines that call for the early use of sodium glucose cotransporter 2 (SGLT2) inhibitors, GLP-1 receptor agonists, and finerenone in the care of patients with both chronic kidney disease (CKD) and diabetes.

The guidance focuses on treatment with tecovirimat, pre-exposure prophylaxis and postexposure prophylaxis with the Jynneos monkeypox vaccine, and infection control among persons living with HIV (PLWH).

Brindley Brooks, who founded HS Connect (HSconnect.org), a patient advocacy group for those affected with hidradenitis suppurativa (HS), spoke on key areas of HS comprehension and management that warrant further investigation in clinical research.

A study found cystatin C, renal resistance index, and urinary kidney injury molecule-1 were significantly associated with risk of diabetic kidney disease (DKD) in children and adolescents with type 1 diabetes (T1D).

Children whose parents were more engaged with an intervention focused on obesity saw greater results compared with children whose parents were less engaged.

This retrospective chart review investigated outcomes among patients who are White or Black on a daratumumab regimen for multiple myeloma (MM).

While past research suggests patients with rheumatoid arthritis (RA) are at increased risk for dementia, a Mayo Clinic study claims this is not the case.

On this episode of Managed Care Cast, we speak with the author of an article in the August issue of The American Journal of Managed Care® about the premium tax credits for health insurance purchased through the health care marketplace, which were recently extended for another 2 years with the signing of the Inflation Reduction Act.

A cross-sectional study found that human papillomavirus (HPV) had a higher probability of being diagnosed in women born in the 1980s compared with women born in the 1990s.

The Biden administration plans to shift COVID-19 test and treatment costs from the government to individuals and insurers; an old FDA rule is being used to limit access to contraceptives; study results suggest almost half of cancer deaths are attributable to preventable risk factors.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

A single-blind, parallel, randomized clinical trial found that a continuous positive airway pressure (CPAP) machine was more effective in normalizing polysomnographic parameters and improving quality of life in patients with mild obstructive sleep apnea (OSA) compared with the mandibular advancement device.

A recent cohort study found that two-thirds of patients could transmit SARS-CoV-2 at 5 days since their symptoms began; the median infectiousness duration in the sample was 5 days.

Despite intranasal corticosteroid (INCs) being a treatment mainstay for chronic rhinosinusitis with nasal polyps, there are ongoing high rates of nonadherence, which can affect treatment efficacy, according to this study’s authors.

Researchers found automated foot strike detection is viable for smartphone-based fall risk classification in patients with lower limb amputations.

CDC Director Rochelle Walensky, MD, MPH, called public guidance during the COVID-19 pandemic “confusing and overwhelming”; CVS, Walgreens, and Walmart were ordered to pay $650.6 million to 2 Ohio counties after improperly dispensing prescription painkillers; a new screening method can detect extra or missing chromosomes in embryos and fetuses within hours.

Investigator Global Assessment score of very severe atopic dermatitis (AD) was associated with dupilumab discontinuation due to adverse effects, although generally adequate 1-, 2-, and 3-year drug survival rates were also observed.

Most participants were able to complete the assessments at home, and their scores correlated well with in-clinic assessments.

Adult patients from dermatology clinics affiliated with 2 Midwest universities were evaluated for their ability to differentiate skin cancer by sight and for their skin cancer knowledge.

Researchers achieved successful reactivation of pancreatic stem cells to become insulin expressing, suggesting future potential for replacing destroyed beta cells in patients with type 1 diabetes with newborn insulin-generating cells.

The FDA Wednesday approved betibeglogene autotemcel (Zynteglo), the first cell-based gene therapy for the treatment of adult and pediatric patients with beta-thalassemia who require regular red blood cell transfusions.

A new case report highlights the potential benefits of risk assessment for women with a family history of autoimmune diseases, such as systemic lupus erythematosus (SLE), who are considering the human papillomavirus (HPV) vaccine.

A study found that adolescents who were more physically active had better sleep quality and heart rate variability than those who were sedentary.

Value management, theranostics, clinical trial access, and a mobile pharmacy are major innovations being integrated into independent community oncology practices, as highlighted at the Quality Cancer Care Alliance Summer 2022 National Leadership Summit.

Patient engagement solutions facilitate active care participation, but several myths persist that hinder their adoption and implementation.

A new FDA rule will allow hearing aids to be purchased without prescriptions; the FDA has received more than 48,000 reports of faulty Philips respiratory devices between May and July; HHS has extended postpartum Medicaid in Hawaii, Maryland, and Ohio.

The new report reverses previous research suggesting that White men who consumed large amounts of gamey meat and rich foods were most at risk.