Patients and Parents Impacted by SMA May Be Optimistic About Prenatal Testing, Therapies
September 2nd 2022As the feasibility of phase 1 clinical trials for prenatal spinal muscular atrophy (SMA) therapies is explored, patient and parent input on prenatal testing and possibly treatment is a valuable tool for guiding research discussions.
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Systematic Approaches to Patient Educational Needs May Benefit Those With Bleeding Disorders
September 2nd 2022Nurse-led education is an essential aspect of care for patients with bleeding disorders, but there is currently a lack of research on specific strategies to improve patient self-management through education.
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New studies have linked a diet of ultra-processed food to a higher risk of colorectal cancer and to an overall risk of mortality; the CDC endorsed the updated booster shots from Moderna and Pfizer-BioNTech for use against the omicron variant; South Carolina Department of Corrections and Pear Therapeutics are teaming up to support inmates recovering from substance use disorders.
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Dr David Koren Discusses Response to the Monkeypox Public Health Emergency
September 2nd 2022David E. Koren, PharmD, MPH, BCPS, AAHIVP, FIDSA, infectious disease clinical pharmacist at Temple University Hospital, speaks on gaps in monkeypox vaccine availability and access and steps to improve response to the public health emergency.
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Results of Macitentan in PAH From SERAPHIN OL Echo Earlier Trial Safety Data
September 1st 2022This open-label extension of the SERAPHIN trial evaluated the long-term safety and tolerability of a small daily dose of the endothelin receptor antagonist against pulmonary arterial hypertension (PAH) among patients from the original study.
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Wide Variation Found in UK Prescribing Guidance for Preferring Low-Carbon Asthma Inhalers
September 1st 2022Understanding if local prescription patterns are influenced by guidance could help policymakers understand what is needed to further encourage a shift to asthma inhalers with less of a climate impact.
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Olipudase alfa (Xenpozyme) was granted FDA approval for patients with Acid Sphingomyelinase Deficiency (ASMD); Moderna and Pfizer-BioNTech’s bivalent COVID-19 vaccines are each authorized for use as a booster dose; people with type A blood have an 18% higher risk of stroke before age 60, compared with other blood types.
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Hemoglobin Improvement Correlates With Better HRQOL in Paroxysmal Nocturnal Hemoglobinuria
September 1st 2022Post hoc analyses of the phase 3 PEGASUS trial found that clinical and hematological improvements were associated with better patient-reported fatigue and physical function outcomes in paroxysmal nocturnal hemoglobinuria, for an overall bettering of health-related quality of life (HRQOL).
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Breathing Exercise Can Help With Fatigue, Daytime Sleepiness in Patients With OSA
August 31st 2022A randomized, controlled, experimental study found that a breathing exercise decreased fatigue and daytime sleepiness at the end of the fourth and eighth weeks of an intervention in patients with obstructive sleep apnea (OSA).
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US life expectancy fell by nearly a year in 2021 to 76.1 years; Pfizer’s COVID-19 pill reduced the number of hospitalizations and deaths among older adults during the Omicron surge in Israel; current smokers were found to have thicker, heavier, and weaker hearts compared with nonsmokers.
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Bradykinin Level Displays Biomarker Benefit in Nasal Polyposis
August 30th 2022With evidence lacking on the role of inflammation in nasal polyposis (NP), this study investigated the role of 2 potential biomarkers in the nasal secretions of patients who have NP concomitant with aspirin-exacerbated respiratory disease.
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Immune Responses to ART Vary by Regimen Among Individuals With Advanced HIV
August 30th 2022People with advanced HIV initiating bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) were more likely to reach CD4 cell count levels of 200 cells/mcL or higher compared with those initiating other antiretroviral therapy (ART) regimens.
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Milken Institute's Sarah Wells Kocsis Outlines How to Improve Earlier Detection of CKD
August 30th 2022Sarah Wells Kocsis, MBA, is co-author of the Milken Institute report, “Chronic Kidney Disease: Finding a Path to Prevention, Earlier Detection, and Management.” She spoke to The American Journal of Managed Care® about the findings of the report and how they can be incorporated into care for patients with chronic kidney disease (CKD).
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Wearing Glasses Inversely Associated With COVID-19 in Unadjusted Analysis
August 30th 2022A cohort study found that there was an inverse association between COVID-19 infection and wearing glasses in an unadjusted analysis, although this association was not identified when adjusting for confounders.
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House members in South Carolina will debate a total ban on abortions with no exceptions for rape or incest; the World Health Organization claimed that the monkeypox outbreak could be eliminated in Europe, citing slowing case counts; a study found that drinking black tea was associated with lower mortality risk.
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Replacing White Bagging Mandates With Market Competition Will Improve Patient Outcome
August 30th 2022Wayne Winegarden, PhD, of the Pacific Research Institute, explains the harm that white bagging policies cause health systems and how replacing them with new measures to boost market competition could help patients.
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