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The approval came exactly 2 months after results from the landmark DESTINY-Breast04 trial showed that the antibody drug conjugate reduced the risk of disease progression or death by 50% compared with chemotherapy for HER2-low patients with both hormone receptor (HR)–positive and HR-negative disease.

The study found that patients with Hodgkin lymphoma (HL) were at an increased risk of any mental health disorder, which was associated with worse long-term outcomes.

This study investigated the potential for postoperative recurrence of chronic rhinosinusitis with nasal polyps (CRSwNP) as measured against B7-H4 expression.

New data show the stark contrast between untreated infants with type 1 spinal muscular atrophy (SMA) and those who received risdiplam.

In this case report, a 50-year-old female patient, with a family history of lung cancer, received a diagnosis of multiple myeloma (MM) following presentation with an apical lung mass.

Patients with Parkinson disease (PD) exhibited significant improvement in measurement scales for depression and anxiety when treated with subthalamic nucleus deep brain stimulation.

With adherence estimated at less than 50% in children, adolescents, and young adults, a recent study stresses the importance of treatment adherence for patients with sickle cell disease receiving hydroxyurea and the benefit for those who do.

The findings can have important implications for shared decision-making between providers and their patients, as well as for future trials of treatments for the disease.

Cow's milk is the most common food trigger for eosinophilic esophagitis (EoE), a chronic inflammatory disease caused by type 2 inflammation.

Researchers developed a framework to pull high-resolution digital phenotypes from wearable devices and use them to predict the risk of cardiometabolic disease.

This UK study looked at the use of telehealth to deliver virtual home assessments for occupational therapy services; the authors also created guidelines to support additional work in this area.

From 2001 to 2019 in Europe, overall chronic obstructive pulmonary disease (COPD) prevalence has increased for females and COPD mortality has decreased more so for men than women, according to the results of a recent study.

Still, investigators say there are gaps in spinal muscular atrophy (SMA) screening protocol that need to be filled.

New real-world evidence on non–small cell lung cancer (NSCLC) aligns with the results of a 2017 clinical trial.

Patients with asthma and all types of obesity, or with all types of obesity and physical inactivity, have an increased risk for limited activity of daily living, according to the results of a recent study.

Brindley Brooks, who founded HS Connect (HSconnect.org), a patient advocacy group for those affected with hidradenitis suppurativa (HS), spoke on the need for awareness among physicians and patients on the clinical features of HS in regard to both physical and psychosocial burdens.

Pharmaceutical Research and Manufacturers of America (PhRMA) is threatening swift retaliation if a reconciliation package that includes drug pricing is passed; New York health officials urge polio vaccinations after polio virus was found in 7 wastewater samples; conjoined twins in Brazil were separated via surgery using virtual reality.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Both the ZUMA-7 trial for axicabtagene ciloleucel—approved for second-line treatment earlier this year—and the TRANSFORM trial for lisocabtagene maraleucel showed significant improvement over standard of care for large B cell lymphoma (LBCL), while the BELINDA trial for tisagenlecleucel did not.

US cases of monkeypox have risen to 6600, and Thursday's declaration aims to provide enhanced testing, treatment, and vaccine capabilities nationwide.

The recommendations follow the World Health Organization’s recent update to its classifications of central nervous system (CNS) tumors to now include a structure for pediatric patients with CNS tumors.

The findings, coming from the phase 3 SEQUOIA study, found that the next-generation, selective Bruton tyrosine kinase inhibitor had superior efficacy versus chemoimmunotherapy and demonstrated an acceptable safety profile among 600 older patients with comorbidities.

A new trial has found that patient management through remote means could reduce all-cause mortality and hospitalizations for heart failure (HF) in patients with renal impairment.

Compared with sensor-augmented pump therapy, closed-loop insulin delivery increased glucose time in range and reduced hypoglycemia episodes but detracted from sleep quality.

Previous studies have produced heterogeneous results on next-generation flow (NGF)-based minimal residual disease (MRD) detection, despite improvements to the method’s reproducibility and sensitivity, prompting the present authors to investigate its clinical utility.

President Joe Biden signed an executive order to help people travel between states for an abortion; Eli Lilly was ordered to pay $61 million after allegedly underpaying the Medicaid drug rebate program; CVS plans to acquire or take a stake in a primary care industry by the end of 2022.

A retrospective observational study found that many US federal holidays and holiday eves were associated with changes in sleep duration, decreases in sleep consistency, and later sleep onset and offset.

New study findings show suboptimal HIV and sexually transmitted infection (STI) testing rates among sexual and gender minority individuals in the state, contrary to CDC guidelines.

The combination is approved to treat hepatocellular carcinoma (HCC), but this case report suggests it can also work for combined HCC and cholangiocarcinoma (CHC).

Cardiovascular disease (CVD) has, over time, becoming the leading cause of death for patients with early-stage classic Hodgkin lymphoma (cHL), surpassing the risk of death from cHL and other cancers.