Lower Risk of Cardiovascular, Metabolic Outcomes Associated With Rituximab for Pemphigus Treatment
December 8th 2022Patients with pemphigus reported lower risk of myocardial infarction and stroke, among other cardiovascular and metabolic outcomes, when treated with rituximab compared with the first-line corticosteroid-sparing agents azathioprine and mycophenolate mofetil.
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Using Risk Factors to Guide CAR T Approach Before, After Infusion in B-ALL
December 8th 2022This paper follows the 10-year remission mark for the first child treated with CD19-targeted CAR (chimeric antigen receptor) T-cell therapy for B-cell acute lymphoblastic leukemia (B-ALL), adding promise to the notion that the technology can provide long-term durable remissions in patients who are highly refractory to chemotherapy.
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Dr Jose P. Leone Highlights the Importance of Breast Cancer Awareness for Male Patients
December 8th 2022Jose P. Leone, MD, director of the program for breast cancer in men at the Dana-Farber Cancer Institute and assistant professor of medicine at Harvard Medical School, shares why patients and providers need to pay more attention to how breast cancer impacts male patients.
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Cannabis Used With ICIs Appears to Have No Impact on NSCLC Outcomes
December 7th 2022Differences in overall survival between cannabis users and those who did not use the plant were small and could be explained by differences in the make-ups of the 2 cohorts of patients with non-small cell lung cancer, researchers said.
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DESTINY-Breast Data Add to Accolades for Trastuzumab Deruxtecan
December 7th 2022A highlight of day 2 at the San Antonio Breast Cancer Symposium was the morning presentation of a pair of studies highlighting the ongoing survival benefit associated with trastuzumab deruxtecan in metastatic breast cancer.
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Dr Dawn Hershman Discusses Tactics to Increase Drug Adherence in Clinical Trials
December 7th 2022Dawn L. Hershman, MD, an oncologist from Columbia University, shared insight into the current challenge of ensuring drug adherence within clinical trials and how this adherence can impact the quality of care for patients in real-world settings.
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Safety and Efficacy of New Hemophilia Treatments Are Most Important, Patients Report
December 7th 2022Safety and efficacy were the most important factors for patients with hemophilia learning about gene therapies, although more research is needed to see how collaboration between providers and patients contributes to the best outcomes.
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Assessing Frequency of Orthostatic Hypotension in Patients With Parkinson Disease
December 7th 2022Frequency of orthostatic hypotension among Ethiopian patients with Parkinson disease (PD) was shown to be higher than that among healthy controls, with a higher proportion of constipation, urinary urgency, and nocturia symptoms reported in those with PD.
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Dr Irene Kang Shares Cognitive Impairment Results From the RxPonder Breast Cancer Study
December 7th 2022Irene M. Kang, MD, from City of Hope, shared some of the results from her analysis of cognitive impairment in women with breast cancer who participated in the RxPonder study, which assessed which patients would benefit most from chemotherapy.
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CMS proposed a rule to streamline the prior authorization process and expand health information access; a scathing report urged the FDA to consider restructuring and potentially dividing the agency; the Institute for Healthcare Improvement (IHI) and American Medical Association (AMA) are coleading the Rise to Health Coalition.
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Dr Emma Searle Previews MajesTEC-2 Data to Be Presented at ASH 2022
December 7th 2022Emma Searle, PhD, consultant hematologist, The Christie Hospital NHS Foundation Trust, touches on key points learnt from MajesTEC-2 data and other data to look forward to at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition.
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Patients With CKD Report Burden Could Improve Through Communication With Physicians
December 7th 2022Speaking with patients diagnosed with chronic kidney disease (CKD) about the burdens associated with care could help improve understanding of the disease and their communication with health care professionals.
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Financial Toxicity From Cancer Is a Patient-Facing Problem, MSK’s Chino States
December 6th 2022Costs are an adverse effect of treatment just like any other adverse effect, with slightly more patients worried about the financial impact of their cancer diagnosis than they are about actually dying from their disease, noted Fumiko Chino, MD, of Memorial Sloan Kettering (MSK) Cancer Center.
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Primary Care Clinicians Can Embrace CGM Implementation With Support, Study Finds
December 6th 2022Patients with diabetes may benefit from continuous glucose monitoring (CGM) as a standard of care in the primary care setting, according to a recent study that assessed clinicians’ attitudes toward prescribing these tools.
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Pharmacists Challenged With Real-world Situations That May Affect ICI Outcomes
December 6th 2022Can a patient with metastatic cancer on immune checkpoint inhibitor (ICI) therapy use acetaminophen for pain? What about medical marijuana? And does the gut microbiome play a role? With more than a decade of real-world experience with ICIs, pharmacists learned about the potential role of these and other factors during a session at the 2022 American Society of Health-System Pharmacy Midyear Clinical Meeting & Exhibition.
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COVID-19 Mortality Risk More Than Doubled Among Homeless Patients
December 6th 2022A cross-sectional study showed that patients experiencing homelessness were at more than 2-fold greater age-adjusted mortality risk due to COVID-19 compared with the general population, with these increased risks observed across race/ethnicity and sex status.
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Glucose-Lowering Drugs May Reduce Risk of COVID-19–Related Adverse Events in Patients With Diabetes
December 6th 2022Patients with diabetes who reported use of sodium-glucose cotransporter-2 inhibitors, glucagon-like peptide-1 receptor agonists, or metformin prior to COVID-19 infection were associated with lower COVID-19–related adverse outcomes during hospitalization.
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