Moderna Receives FDA Nod for Single-Dose RSV mRNA Vaccine
May 31st 2024The FDA approved mRNA-1345, a Moderna vaccine for the treatment of respiratory syncytial virus (RSV). This single-dose vaccine offers protection against lower respiratory tract disease in adults over 60 years, with data suggesting long-term effectiveness.
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There has been a lack of visible progress from RECOVER, the $1.6 billion initiative launched by the National Institutes of Health to research long COVID; the CDC has detected a third human case of bird flu linked to sick dairy cows; small businesses and their workers are struggling to receive weight-loss drug insurance coverage.
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History of Oral Contraceptive Use, Gene Variant May Increase Risk of FFA
May 31st 2024A case controlled study suggests a gene variant may offer some protection from frontal fibrosing alopecia (FFA), but only if there is no prior history of oral contraceptive pill use, which appears to increase the risk for carriers of this variant.
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Hypersomnia, Mental Health, Inequities Among the Highlighted Topics at SLEEP 2024
May 30th 2024The annual conference taking place from June 1 to June 5, 2024, will feature sessions on the relationship between mental health and sleep, artificial intelligence in sleep, and different sleep conditions.
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Durvalumab's High Costs Hinder Global Uptake for Stage III NSCLC Maintenance Therapy
May 30th 2024This international study, incorporating data from the US, Brazil, Singapore, and Spain, shows that durvalumab as maintenance therapy for use against non–small cell lung cancer remains a cost-prohibitive treatment option.
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What We’re Reading: Clinical Trial Diversity; Nicotine-Like Vape Chemicals; Weight-Loss Drug Tracker
May 30th 2024Despite diversity enrollment goals, clinical trials funded by the National Institutes of Health (NIH) often enroll fewer patients among underrepresented racial groups; nicotine alternatives used in vapes may be more potent and addictive than nicotine itself; telehealth company Ro built a drug supply tracker to help patients find available doses of GLP-1 drugs.
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From Polypharmacy to Personalized Care: Dr Nihar Desai Discusses Holistic Cardiovascular Care
May 30th 2024In this episode of Managed Care Cast, Nihar Desai, MD, MPH, cardiologist and vice chief of Cardiology at the Yale School of Medicine, discusses therapies for cardiovascular conditions as they relate to patient adherence, polypharmacy, and health access.
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Patients With AGA Treated With PRP Display Hair Regrowth, Potential Microbiome Rebalance
May 30th 2024Platelet-rich plasma (PRP) treatment increased hair regrowth in patients with androgenetic alopecia (AGA) and may help rebalance the scalp microbiome, although the link between the microbiome changes and hair growth needs future investigations.
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Patient Characteristics Affect AI Performance in Breast Cancer Screening
May 29th 2024A US study found that a commercially available artificial intelligence (AI) algorithm for breast cancer screening produced more false-positives in Black patients and people with denser breasts, highlighting the importance of diverse datasets in training AI algorithms to reduce health care disparities.
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Dr Ravin Ratan on Advancing Sarcoma Care at ASCO 2024
May 29th 2024In this interview ahead of the 2024 American Society of Clinical Oncology annual meeting (ASCO), Ravin Ratan, MD, MEd, The University of Texas MD Anderson Cancer Center, discusses study data he is excited to hear more about on the combination of trabectedin and low-dose irinotecan for relapsed/refractory Ewing sarcoma.
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Immunological Events Indicated in Onset of Hypersomnolence Disorders, Study Finds
May 29th 2024Findings from a retrospective study suggested a possible causal relationship between prior infection and the development of hypersomnolence disorders such as narcolepsy and idiopathic hypersomnia, but more research is needed.
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Patients With Diabetes and Heart Failure May Face Worse Outcomes, Increased HFpEF Risk
May 29th 2024According to new research from Jordan, patients with both heart failure (HF) and diabetes had a higher prevalence of HF with preserved ejection fraction (HFpEF), elevated cholesterol, low-density lipoprotein, and impaired kidney function.
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Pegcetacoplan Contributes to Better Outcomes in PNH vs Other Treatments
May 29th 2024An analysis of 2 phase 3 trials supporting the use of pegcetacoplan (PEG) in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) assessed the benefits of this treatment compared with eculizumab (ECU) and supportive care measures.
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Scientists are worried that fertilized hen eggs remain the main ingredient for the H5N1 bird flu vaccine; an increased risk of preterm delivery and stillbirth exists in the US due to the worsening climate; health care executives are discussing whether they should bring in outside consultants or hire more employees in preparation for cyberattacks.
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Primary Cicatricial Alopecia Connected to Increased Risk of Endocrine, Metabolic Diseases
May 28th 2024A study using a large Korean health database found that people with a rare hair loss disorder called primary cicatricial alopecia were more likely to also have additional health problems like diabetes and high blood pressure compared with people who had other hair loss conditions or no hair loss at all.
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