Kimberly Rath, PharmD, is a freelance health writer who previously worked as a clinical pharmacist with Elevance Health for a decade. She has also worked for Amerigroup and Sentara Group.
Genetic Study Establishes Causal Link Between RA and Interstitial Lung Disease Risk
A combined assessment of genetic, serologic, and clinical factors may enhance early recognition of patients with RA who are most at risk for ILD.
Ibrutinib-Based Frontline Regimens Narrow the Survival Gap in CLL
Modern ibrutinib-based approaches substantially narrow the traditional survival gap observed in CLL.
Higher Food Inflammation Index Score Tied to Greater MASLD Risk
A national survey analysis suggests a link between higher Food Inflammation Index scores and metabolic liver disease.
CD19 CAR T-Cell Therapy Shows Promising Activity in Richter Transformation
CAR T-cell therapy achieves meaningful responses and survival gains in this aggressive CLL complication.
New Evidence Strengthens Case for Modifiable Risk Factors in Multiple Sclerosis
Diet and metabolic health may have causal effects on MS development, suggesting that a healthy weight, controlling glucose levels, and reducing red meat intake may delay or prevent onset.
Balancing Efficacy and Safety in BTKi Therapy
Despite improved selectivity, real-world data point to persistent cardiovascular challenges even with next-generation BTKi therapies.
Disparities in Pneumonia and Fibrosis Mortality Persist Across the US
A national analysis of CDC data over 25 years revealed persistent sex, racial, and regional disparities in pneumonia and pulmonary fibrosis mortality.
Shared Molecular Pathways Link IPF and RA-Associated Lung Disease
An IPF-derived biomarker profile shows a reproducible association with ILD risk across three RA cohorts.
Fixed-Dose Serplulimab Strategy Supported by Comprehensive Pharmacokinetic Analysis
A new population pharmacokinetic and exposure-response analyses shows no added efficacy or safety benefit from higher doses of serplulimab.
Metabolic Reprogramming Takes Center Stage in Fibrotic Lung Disease
Metabolic intermediates were identified as active participants in fibrosis progression and potential targets for next-generation therapies.
Microbial Imbalances, Structural Changes Linked With Olfactory Dysfunction in MS
Structural and microbial findings point to a potential nasal-brain immune connection in patients with multiple sclerosis (MS).
Integrated RA Pathway Improves Outcomes in Real-World Study
A multidisciplinary approach that includes addressing social determinants of health reduces time to remission despite higher initial costs.
Serum Spectroscopy Reveals Prognostic Risk Factors in CLL
Serum biochemical fingerprints can stratify chronic lymphocytic leukemia (CLL) outcomes and uncover heterogeneity within molecularly defined low-risk disease.
Prospective Evidence Supports Tumor-First Multigene Testing in Ovarian Cancer
Tumor-first multigene testing boosts diagnostic accuracy, minimizes duplication, and aligns with professional society recommendations for integrated sequencing.
Altered Trace–Metal Homeostasis Linked to CKD Pathogenesis
Metallomic correlations suggest environmental and metabolic metals act together to accelerate renal damage.
Tryptophan Metabolism Linked to csDMARD Response in Rheumatoid Arthritis
Integrated data suggest higher tryptophan activity is associated with reduced inflammation and improved outcomes in RA.
Network Disconnection, Not Lesion Volume, Drives MS Cognition
Lesion-based disconnectome mapping suggests that the pattern, not the quantity, of brain damage determines cognitive outcomes in patients with MS.
Novel Machine Learning Model Improves MASLD Detection in Type 2 Diabetes
A machine learning–driven web tool based on 13 standard patient metrics demonstrates strong predictive performance for MASLD, supporting early clinical intervention.
Real-World Data Highlight Value of NOTCH1 Screening in CLL
Patients with NOTCH1 mutations derive greater benefit from BTK inhibitor treatment than from immunochemotherapy for chronic lymphocytic leukemia (CLL).
Wide Gaps in DMARD Adherence Reporting Complicate Rheumatoid Arthritis Care
DMARD nonadherence rates in patients with RA range from 0% to 100%, with inconsistent measurement tools and few validated interventions.
Real-World Evidence Supports Chemoimmunotherapy in ES-SCLC With Poor PS
Atezolizumab or durvalumab, combined with platinum-doublet regimens, delivered superior responses and survival in patients often excluded from clinical trials.
Dual JAK Inhibition Demonstrates Efficacy in Progressive Nonsegmental Vitiligo
Oral upadacitinib combined with topical ruxolitinib cream may be a promising therapeutic approach for patients with progressive nonsegmental vitiligo.
Lubiprostone May Offer Renoprotection in CKD
Treating constipation with lubiprostone may confer renal benefits in chronic kidney disease by modulating microbiome-driven pathways.
Epcoritamab Shows Promise in Case of Richter Syndrome
Findings suggest bispecific CD3xCD20 therapy may offer an option for patients with Richter syndrome who are ineligible for transplant or CAR T-cell Therapy.
AI-Driven Research Toolkit Links Aging Biology and Fibrotic Disease
A recent study outlines how artificial intelligence advancements are transforming research and therapeutic strategies for idiopathic pulmonary fibrosis.
Mixed Outcomes From Multidisciplinary Sarcoma Clinic
Multidisciplinary care influenced therapy choices but did not substantially shorten treatment delays for patients with sarcoma.
Refined iRR6 Model Improves Risk Stratification in Intermediate-1 Myelofibrosis
Underdosing, poor spleen response, and transfusion dependence drive inferior survival outcomes in intermediate-1 myelofibrosis.
Senescent Fibroblasts in IPF Linked to NUDT21 Deficiency
Findings reveal that alternative polyadenylation regulates SASP factors and may fuel age-related pulmonary fibrosis.
Expanding Treatment Options for Chronic Spontaneous Urticaria
The chronic spontaneous urticaria treatment landscape has shifted in recent years, with expanding treatment options for patients with refractory disease.
Vaccination Remains Essential in Multiple Myeloma Despite Impaired Responses
Despite reduced immune responses, immunization lowers infection rates and remains central to supportive care in patients with multiple myeloma.