Genetic, Inflammatory Predictors of Nondilated Left Ventricular Cardiomyopathy Progression
Genetics played a major role in predicting worsening LVEF, progressing to a dilated cardiomyopathy phenotype, and a combined end point of both.
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ICYMI: Highlights From the 2025 ASPC Congress on CVD Prevention
The meeting included new evidence and expert insights on hormone therapy, AI, and the expanding role of GLP-1 therapies in cardiovascular care.
FDA Approves Intranasal Etripamil for Type of Arrhythmia
Intranasal etripamil was approved to self-treat episodes of paroxysmal supraventricular tachycardia, supported by phase 3 RAPID trial data.
FDA Approves Once-Monthly PCSK9 Injection for LDL-C Reduction
Lerodalcibep-liga subcutaneous injection is now approved for adults with hypercholesterolemia, including heterozygous familial hypercholesterolemia.
Team-Based Strategies Advance Cardio-Renal-Metabolic Health
Experts convened in Cleveland, Ohio, on November 11, 2025, to discuss the evolution of cardio-renal-metabolic care from treatment of individual diseases to team-based, population-focused care.
ICYMI: Highlights From ACC 2025
Semaglutide, sotatercept, and bentracimab trials were attendees’ main focus at the American College of Cardiology 2025 Annual Scientific Session.
Digital Innovation and New Drugs Converge to Transform CRM Care
Academic and clinical experts convened in New Haven, Connecticut, on October 30, 2025, to discuss the potential of coordinated care and prevention to manage cardio-renal-metabolic (CRM) disease.
Transforming Population Health for Diabetes and Kidney Disease via Systems of Excellence
Clinicians and health system leaders met in Cleveland, Ohio, on October 23, 2025, to share improvements to value-based care in diabetes and chronic kidney disease.
Once-Monthly Maridebart Cafraglutide Shows Up to 16% Weight Loss
A phase 2 trial demonstrated substantial weight loss with the long-acting peptide–antibody conjugate, as well as other cardiometabolic improvements.
Technology Drives Innovation, Accessibility When Treating Chronic Kidney Disease
Experts met in Park City, Utah, on October 7, 2025, to discuss how new technologies can help address chronic kidney disease.
Diabetes Tied to Increased Risk of Sudden Cardiac Death
Patients aged 30 to 40 years with type 1 diabetes had the highest risk of sudden cardiac death, according to 2010 data from Denmark.
Managing Cardio-Renal-Metabolic Diseases Requires Multifactorial Approach
Speakers at the Institute for Value-Based Medicine event held September 18, 2025, in Nyack, New York, spoke about methods of managing cardio-renal-metabolic disease.
Setting the Stage for Collaborative Care to Address CKM Syndrome
Payer and health system leaders convened in Pittsburgh, Pennsylvania, on September 9, 2025, to discuss the interconnected health conditions of cardiovascular-kidney-metabolic (CKM) syndrome.
WHO Publishes GLP-1 Guidelines for Obesity Treatment
The guidelines highlight the need for lifelong obesity management, early diagnosis, comorbidity prevention, and patient-centered care.
Asundexian Reduces Recurrent Ischemic Stroke Without More Bleeding
Phase 3 OCEANIC-STROKE data show how asundexian offers a potential new secondary stroke prevention option.
Stress Echo Reveals Hidden Risks in Asymptomatic Hypertrophic Cardiomyopathy
Long-term data suggest stress echocardiography can uncover impaired exercise capacity and predict worse outcomes in patients.
FDA Approves Sibeprenlimab for Immunoglobulin A Nephropathy
Sibeprenlimab gains accelerated approval from the FDA for IgA nephropathy, showing significant proteinuria reduction and offering convenient self-injection treatment.
Real-World Risks of Mavacamten Use for Obstructive Hypertrophic Cardiomyopathy
After 8 months of treatment with mavacamten, 5% of patients developed new atrial fibrillation or flutter and 4% developed heart failure.
Extreme Heat Raises Mortality Risk for Veterans With Cardiometabolic Disease
A case-crossover study found that extreme heat increased mortality between 10% and 18%, with higher risks in vulnerable groups.
Provider Shortages in Nevada Leave Gaps in Cardiovascular Care: Svetlana Barbarash, MD
Svetlana Barbarash, MD, outlines the lack of cardiologists and transplant services in Las Vegas and the policy changes needed to close gender gaps in care.
Women’s Subtle Arrhythmia Symptoms Are Often Overlooked: Svetlana Barbarash, MD
Svetlana Barbarash, MD, explains how better education, digital monitoring tools, and coordinated care can improve arrhythmia detection and outcomes.
BPA Exposure Linked to 127 Million Global Metabolic Disease Cases
Research shows a sharp rise in bisphenol-attributable metabolic disease since 2000, with annual costs exceeding $250 billion in North America.
2025 Hypertension Guideline Updates Presented at AHA Scientific Sessions
Updated guidelines set lower systolic blood pressure goals, expanded risk-based treatment, and call for stronger implementation to close care gaps.
Papillary Muscle Scarring May Predict Cardiac Death in Dilated Cardiomyopathy
Papillary muscle scarring has a substantial association with both cardiovascular mortality and arrhythmia.
Can a Coffee a Day Keep AFib Away?
Researchers urged caution in interpreting DECAF Trial results that suggest daily coffee intake is linked to a lower risk of atrial fibrillation recurrence.
CAVIAR: Alirocumab Safely Lowers Cholesterol After Heart Transplant
The trial did not meet its primary end point for reducing plaque progression.
POLY-HF: Polypill Boosts Heart Function, Adherence in Heart Failure
Combining 3 standard therapies into a single pill improved outcomes for adults with heart failure with reduced ejection fraction.
Stress Cardiac MRI May Catch Missed Angina Diagnoses
New research suggests stress cardiac MRI could help diagnose angina and improve quality of life for patients whose arteries appear clear on angiography.
Interventions to Advance Equity in Pediatric Cardiovascular Care
Only 4% of NIH prevention projects target health disparities, revealing a major gap between equity research and real-world implementation.
Oral PCSK9 Inhibitor Enlicitide Matches Injectables in Lowering LDL Cholesterol
In a phase 3 trial, the investigational oral PCSK9 inhibitor enlicitide reduced LDL cholesterol by nearly 60% in adults with or at risk for ASCVD.