- Center on Health Equity & Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Understanding Immune Thrombocytopenia: Pathophysiology, Classification, and Differentiation
A panelist discusses how immune thrombocytopenia (ITP) is characterized by isolated low platelet counts due to autoimmune destruction, with classification based on duration (acute, extended, or chronic) and severity of thrombocytopenia.
Immune thrombocytopenia (ITP) is characterized by an isolated low platelet count while maintaining normal white blood cell count and hemoglobin levels. This autoimmune disorder involves peripheral destruction of platelets through autoantibodies, though the exact mechanism behind this development remains somewhat mysterious to medical professionals.
ITP is classified based on duration of thrombocytopenia: acute phase (1-3 months), extended phase (3 months to 1 year), and chronic phase (beyond 1 year). Classification also considers platelet count severity, with severe thrombocytopenia defined as counts below 10,000, moderate between 10,000-50,000, and mild ranging from 50,000 to normal limits.
Most ITP patients present with severely low platelet counts, typically less than 10,000. The severity threshold classifications help guide treatment approaches and risk assessment, with patients below 10,000 requiring more urgent intervention due to increased bleeding risks.
Ovarian Cancer Survival Gaps Persist Across Racial, Ethnic Groups
May 27th 2025Abstracts published ahead of the 2025 American Society of Clinical Oncology Annual Meeting found persistent ovarian cancer survival disparities among racial and ethnic subgroups, particularly within disaggregated Asian American, Native Hawaiian, and Pacific Islander populations.
Read More
