Dupilumab Efficacy in AD Not Affected by Age of Disease Onset
October 25th 2022Dupilumab exhibited similarly significant and sustained improvements in atopic dermatitis (AD) signs, symptoms, and quality of life of adult patients with moderate to severe AD, regardless of age of disease onset, compared with placebo.
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CVS Health and a digital diagnostic startup will produce at-home tests for vitamin D, Lyme disease, sexually transmitted infections, and thyroid function; researchers identified 42 genetic variants associated with dyslexia; FDA plans updated mammogram regulations to help women with dense breasts.
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Are NK-Cell–Based Treatments the Next Approach in Immuno-Oncology?
October 25th 2022Highlighting their ability to quickly destroy malignant cells without antigen specificity, natural killer (NK) cells have been identified as an opportunity for use, particularly in cases where T cells are not effective.
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Updated Clinical Practice Guidelines for CDI Show Improved Outcomes, but Adherence Issues Remain
October 25th 2022Improved outcomes associated with fidaxomicin compared with vancomycin suggest benefits from its greater use in Medicare patients, although uptake remains low despite its recommended use.
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Combination of Tremelimumab and Durvalumab Approved by FDA for Unresectable Liver Cancer
October 24th 2022A dual immunotherapy option of tremelimumab, sold as Imjudo, in combination with durvalumab, sold as Imfinzi, was approved by the FDA Monday for the treatment of adult patients with unresectable hepatocellular carcinoma, the most common type of liver cancer.
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Potential Risk Factors Identified for RRT Among Patients With PH
October 24th 2022According to the study authors, acute decompensated pulmonary hypertension (PH) is often accompanied by systemic congestion and right ventricular flow output, and because PH can be accompanied by acute kidney injury, renal replacement therapy (RRT) may be necessary.
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Evaluating Impact of COVID-19 Pandemic on Informal Caregivers of Patients With Parkinson Disease
October 24th 2022Informal caregivers of people with Parkinson disease residing in the United Kingdom discussed challenges faced in providing care during the COVID-19 pandemic, which included risk of infection, lack of access to care, and the impact of lockdown on engaging in activities of daily living.
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Adding Machine Learning to Longitudinal PRO Data May Prove Useful in RA
October 24th 2022In a proof-of-concept analysis, researchers show that machine learning methods paired with longitudinal patient-reported outcomes (PRO) data were able to classify subsequent rheumatoid arthritis (RA) disease activity after beginning treatment with a biologic
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The Biden administration will expand the use of medication to treat substance use disorders to include pregnant women; oversight of the nation’s poorest-performing nursing homes will be tightened; children’s hospitals are filling up with cases of respiratory syncytial virus and other respiratory diseases.
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Dr Melissa O'Connor on Policy Reform to Address Unmet Needs in Home Health
October 23rd 2022Melissa O'Connor, PhD, MBA, RN, FGSA, FAAN, endowed professor in Community and Home Health Nursing, M. Louise Fitzpatrick School of Nursing, Villanova University, and director, Gerontology Interest Group, discussed several policy needs for home health care, including improved caregiver support, updated eligibility criteria for in-home care, and reimbursement for telehealth.
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Contributor: Congress Must Fix Patient Protection Statute Upended by Supreme Court
October 23rd 2022The author, the dean of the College of Ethnic Studies at California State University Los Angeles, says a Supreme Court ruling could upend insurance protections for patients with kidney diseases, disproportionately hurting those who are Black, Hispanic, Asian, and other diverse ethnicities.
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Identifying ASCT-Ineligible Patients Who Could Benefit From CAR T-Cell Treatment
October 22nd 2022Data suggest that the technology may be an option for patients who are ineligible for autologous stem cell transplantation (ASCT) based on certain patient characteristics, prior treatments, stem cell availability, or tumor chemosensitivity.
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