Valproate Exhibits Both Hypnotic, Antiepileptic Properties During Sleep
January 21st 2023In an animal study, researchers found that valproate, a common epilepsy drug, possessed hypnotic and antiepileptic properties during sleep, suggesting that the drug could help improve sleep quality for patients with nocturnal epilepsy.
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Motor Symptoms May Occur 3 Years Before Parkinson Disease Diagnosis, Study Says
January 20th 2023Trouble with balance and holding objects above one's head were just a few of the problems reported by patients 3 years before they received a formal Parkinson disease diagnosis, according to a recent study.
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What We’re Reading: US Hits Debt Limit; More Oversight of Organics; Drug-Resistant Gonorrhea
January 20th 2023As the country hits the debt limit spending on Medicare and Medicaid may be at risk; the Agriculture Department targets fraudulent claims in products labeled as organic; first cases of drug-resistant gonorrhea strain found.
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Examining the Links Between Asthma, Depression During the Pandemic in Canada
January 20th 2023The study sought to identify what factors were linked with developing depression in adults with asthma without a history of the disease, and to identify which factors were associated with recurrent depression during the pandemic in adults with both conditions.
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Early Diagnosis Vital to Prevent Impairment From Pediatric EGIDs
January 20th 2023Although it is well studied in adult patients, there is a lack of research on eosinophilic gastrointestinal disorders (EGIDs) among pediatric patients; a recent study aimed to add to the clinical knowledge of EGIDs in younger patients.
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Tucatinib Plus Trastuzumab Approved for RAS Wild-type, HER2+ Unresectable or Metastatic CRC
January 19th 2023The combination of tucatinib and trastuzumab received accelerated approval from the FDA to treat adults with RAS wild-type, HER2-positive unresectable or metastatic colorectal cancer (mCRC) that advances after treatment with specific types of chemotherapy.
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Fetal Outcomes, Maternal Mortality Vary Among Pregnant Women With Different Types of PH
January 19th 2023A small study conducted in China suggests pregnant women with idiopathic pulmonary arterial hypertension (iPAH) are at higher risk of maternal mortality compared with women with certain other types of pulmonary hypertension (PH).
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Axi-cel Shows Improved Quality-Adjusted Survival Versus Standard of Care in LBCL
January 19th 2023A Q-TWiST analysis of ZUMA-7 trial data suggests that axicabtagene ciloleucel (axi-cel) in the second line is beneficial to quality-adjusted survival and is a viable option for patients with relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy.
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Interstitial Lung Abnormalities Impact OS in NSCLC Patients Receiving CRT, Adjuvant Durvalumab
January 19th 2023Pretreatment interstitial lung abnormalities were associated with worse overall and cause-specific survival in Japanese patients receiving chemoradiotherapy followed by adjuvant durvalumab for locally advanced non–small-cell lung cancer.
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