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Martin Runnström, MD, a fourth-year fellow at the Emory University School of Medicine, describes a study he presented at CHEST 2022 showing a reduced response to a 2-dose immunization series for SARS-CoV-2 among patients using biologics to treat severe asthma or atopic dermatitis.

Experts anticipate a rise in US COVID-19 cases, hospitalizations, and deaths beginning in 3 to 4 weeks; Covis Pharma pushes to keep hydroxyprogesterone caproate (Makena) on the market; more than 1.3 million American adults with diabetes delayed purchasing or skipped or rationed insulin doses due to high costs.

In the Roger C. Bone Memorial Lecture in Critical Care at CHEST 2022, E. Wesley Ely, MD, MPH, of the Vanderbilt University School of Medicine, highlights the need for humanism in the intensive care unit and how the COVID-19 pandemic destroyed what had been built up.

Untreated bleeds often go undocumented during clinical trials, but reporting these bleeding events could provide additional insight into therapy efficacy.

The report found people using continuous monitoring systems spent more time in their target glucose ranges.

Researchers reviewed clinical features of hidradenitis suppurativa and provided strategies to promote earlier identification, differentiation from common mimickers, and timely referrals for multidisciplinary management.

While the prevalence of eosinophilic esophagitis (EoE) is estimated to be 0.5% in the general population, a recent study found that the prevalence was as high as 16.5% in patients with allergic disease.

Prior to the analysis, researchers hypothesized that having localized psoriasis on more visible and/or more sensitive areas, including the face and genitals, would yield a more significant impact on quality of life.

As understanding of COVID-19 evolves and more evidence on treatments emerges, making sense of it can be a challenge for physicians.

Some atopic diseases affect asthma outcomes more than others, said Basil Kahwash, MD, an assistant professor of medicine on the clinical educator track in the Department of Medicine at Vanderbilt University Medical Center, who spoke at CHEST 2022.

A maternal health mobile app helped pregnant women learn more about delivery sanitation, tetanus vaccination, reproductive tract infection symptoms, HIV/AIDS testing, and iron tablet usage.

A digitally delivered targeted intervention of symptom and trigger education, treatment reminders, lifestyle coaching, and healthy lifestyle support demonstrated significant improvements in treatment adherence and related clinical outcomes among Icelandic patients with atopic dermatitis.

The launch of the National Kidney Foundation’s first nationwide registry of patients with kidney disease could help link patient data with laboratory and clinical information.

A cross-sectional study found that socioeconomic status and sleep quality affected the prevalence of multimorbidity in older adults.

The Bill and Melinda Gates Foundation donated $1.2 billion toward eradicating polio worldwide; founders of BioNTech say that cancer vaccines could be available within the next decade; an early increase in flu activity has hit southeast and south-central states hardest according to the CDC.

Results will be presented at an upcoming medical conference.

Vestibular dysfunction was shown to be a determinant of imbalance in Parkinson disease independent from visual and somatosensory processing changes and nigrostriatal dopaminergic losses.

There are several closely watched randomized trials examining catheter-directed therapies for acute pulmonary embolism, according to Parth Rali, MD, an associate professor of thoracic medicine and surgery at the Lewis Katz School of Medicine and director of the Temple University Health System Pulmonary Embolism Response Team.

One poster found patients with uncontrolled asthma had improved outcomes after escalating to triple therapy, while the other found a substantial portion of patients adherent to a dual therapy reported not having controlled asthma.

While more research is needed, obesity does play a role in the response to viral infections as well as immunizations, said Kara Dupuy-McCauley, MD, a pulmonologist at the Mayo Clinic in Rochester, Minnesota.

The first 5 minutes of a patient’s visit with a doctor can help improve communication and build more trusting relationships, explained panelists during a session on lung health disparities in America at CHEST 2022.

Telemedicine may be the future of health care for American Indians and Alaskan Natives who live in tribal communities and remote areas.

Risk of osteoporosis and bone fractures in rheumatoid arthritis (RA) stem from disease-specific causes, disease treatment, and factors that face the general population, according to researchers, who highlighted the importance of assessing risk factors in these patients.

Though typically associated with effects on the joints, rheumatoid arthritis (RA) was found have a pulmonary effect in nearly 3 in 4 patients included in the retrospective, single-center study.

Chronic liver disease and pancreatitis were among the digestive diseases with high increases in incidence and mortality since 2000.

Although no pharmacological treatment offers long-term efficacy or extends survival with Huntington disease at this point, research suggests that stem-cell therapy holds promise in this and other neurodegenerative diseases.

Melissa O'Connor, PhD, MBA, RN, FGSA, FAAN, endowed professor in community and home health nursing, M. Louise Fitzpatrick School of Nursing, Villanova University, and director, Gerontology Interest Group, addressed the impact of food/housing insecurity and other social determinants of health (SDOH) on care outcomes in home health.

Tam C. Phan, PharmD, AAHIVP, assistant professor of clinical pharmacy, USC School of Pharmacy, explains why it's important for pharmacists to learn about and advocate for their patients who are transgender or gender nonbinary.

Despite the obstacles and risks, the review authors conclude that universal chimeric antigen receptor (CAR) T-cell therapy has the potential to play a key role and mitigate some of the limitations associated with autologous CAR T-cell therapy in cancer treatment.

Panelists at an Academy of Managed Care Pharmacy (AMCP) Nexus 2022 session discussed enhanced utilization management strategies to manage the rising cost of specialty drugs, while providing members with support for rare, complex conditions.