FDA Approves Mepolizumab as First Once-Monthly Biologic for COPD With Eosinophilic Phenotype
May 22nd 2025FDA approves mepolizumab (Nucala; GSK) as the first monthly biologic for chronic obstructive pulmonary disease (COPD), significantly reducing exacerbations in patients with an eosinophilic phenotype.
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Supplemental Dental, Vision Benefits May Not Justify MA Payments for VA-Covered Veterans
May 22nd 2025Veterans primarily receiving care through the Department of Veterans Affairs (VA) similarly used dental and vision services under Medicare Advantage (MA) and traditional Medicare, challenging the justification for full MA capitated payments based on supplemental benefits.
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The Role of Pharmacists Expands Beyond Dispensing for Novel Cancer Therapies: Eileen Peng, PharmD
May 21st 2025The advent of novel cancer care therapies such as chimeric antigen receptor T-cell therapy and bispecific antibodies is transforming the role of pharmacists in enhancing patient care.
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Mepolizumab Reduces COPD Exacerbations in Patients With Eosinophilic Inflammation
May 20th 2025New findings from the MATINEE and COPD-HELP studies suggest mepolizumab could reduce exacerbations and improve quality of life in patients with eosinophilic chronic obstructive pulmonary disease (COPD).
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FIBRONEER-ILD: Novel PDE4B Inhibitor Slows FVC Decline in Progressive Pulmonary Fibrosis
May 20th 2025Nerandomilast significantly slowed lung function decline and reduced mortality in patients with progressive pulmonary fibrosis (PPF), with consistent efficacy regardless of background antifibrotic therapy.
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Federal Rule Aimed to Clarify Equity for Mental Health Coverage: Ali Khawar
May 20th 2025Ali Khawar, former Department of Labor official, explains the original intent of a federal rule to reinforce the Mental Health Parity and Addiction Equity Act could be under threat as the Trump administration walks back enforcement.
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MRD Status Guides Consolidation With Cema-Cel in ALPHA3 Trial: Fred Locke, MD
May 20th 2025The ALPHA3 trial is exploring cemacabtagene ansegedleucel's (cema-cel) potential to enhance outcomes in patients who have relapsed/refractory large B-cell lymphoma, particularly those positive for minimal residual disease.
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Health Policy in Flux: Trump Administration Updates
May 20th 2025HHS announces it is taking steps to implement President Trump’s Executive Order on prescription drug pricing. Keep up with the latest moves made in health policy under President Donald Trump's second administration. This timeline will be updated as orders and policy progress.
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Is the US Headed for an Infectious Disease Pandemic?
May 20th 2025In an era that FDA Commissioner Marty Makary, MD, MPH, calls an "epidemic of distrust" toward health institutions, previously contained disease rates are rapidly rising, and vaccination rates are proceeding in the opposite direction.
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Nerandomilast Slows Lung Function Decline in Patients With IPF
May 19th 2025The latest results from the phase 3 FIBRONEER-IPF trial showed consistent benefit of nerandomilast in patients with idiopathic pulmonary fibrosis (IPF) whether or not they were receiving background antifibrotic therapy.
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Sleep Patterns, Predictors, and Pharmacologic Interventions in the ICU
May 19th 2025Research presented at the American Thoracic Society (ATS) 2025 International Conference used FDA-approved tools to see how sleep can impact other parts of recovery for patients in the intensive care unit (ICU).
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The Argument Against Routine Antibiotics for Patients With Nonsevere COVID-19
May 19th 2025Over 500,000 US patients hospitalized with nonsevere COVID-19 saw no clinically significant benefit and potential harm associated with routine early antibiotic treatment, supporting antibiotic stewardship to limit unnecessary use.
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