Experimental RNA Therapy Significantly Reduces Blood Pressure up to 6 Months, Study Says
February 18th 2024Researchers said these findings confirm that zilebesiran can significantly reduce serum angiotensinogen levels, leading to sustained reductions in blood pressure over a 24-hour period, even 6 months post-treatment, though more research is needed for longer-term use.
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Hospitalized Children With Diabetes May Be Able to Continue Safe Use of Home Pumps, Suggest Findings
February 17th 2024Using home insulin pumps when hospitalized was relatively safe compared with hospital-managed pumps and insulin injections among more than 2700 children admitted to a single hospital center.
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Combination Therapies Provide Optimal Hypertensive Control in Patients Taking Ibrutinib
February 17th 2024The retrospective study found patients on Bruton’s tyrosine kinase inhibitors are similar to the general population in the sense that it usually takes at least 2 anti-hypertensive drugs to control blood pressure.
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Health Equity and Access Weekly Roundup: February 17, 2024
February 17th 2024This week in health equity and access includes challenges for independent physicians due to Medicare cuts, inequities in access to State Health Insurance Assistance Program counseling, a study on patient experiences in national health plans, strategies for building trust in cancer care, and increasing breast cancer rates in young Black women.
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FDA Grants Accelerated Approval to Lifileucel, First Cellular Therapy for Advanced Melanoma
February 16th 2024Lifileucel was granted approval for the treatment of adults with unresectable or metastatic melanoma that has been previously treated with other therapies, marking the first approval of a tumor-derived cellular therapy in a solid tumor cancer.
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Swedish Study Links False-Positive Mammograms to Elevated Breast Cancer Risk
February 16th 2024Swedish women with prior false-positive mammograms, particularly those aged 60 to 75 with prior biopsies and low density, show elevated breast cancer risk, necessitating closer monitoring and better screening.
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Carrie Kozlowski: Enhancing Patient Access Amidst Rising Medicaid Disenrollment
February 15th 2024Carrie Kozlowski, OT, MBA, chief operating officer and cofounder of Upfront Healthcare, explains how the company emphasizes personalized engagement to overcome technological, cultural, and social barriers while Medicaid disenrollment rates are increasing.
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Daratumumab-Based Regimen Potential Promising Bridging Therapy for RRMM
February 15th 2024The combination of daratumumab and immumodulatory therapy was evaluated among patients with relapsed/refractory multiple myeloma (RRMM) who have failed prior treatment with immunomodulatory agents, proteasome inhibitors, and daratumumab as monotherapy or in combination.
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Vyvgart Phase 3 Extension Study Data Affirm Long-Term Safety, Efficacy in gMG
February 15th 2024Details from the final interim data analysis of the ADAPT+ study confirm previous findings seen with efgartigimod (Vyvgart) in generalized myasthenia gravis (gMG), the rare neuromuscular autoimmune disease.
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The Federal Trade Commission and HHS will examine generic drug shortage causes; the Biden administration recently dedicated an additional $515 million to a major initiative to study long COVID; cybersecurity experts warn that US hospitals are at risk for attacks and the government is doing little to prevent such breaches.
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In Adolescents With Obesity, FMT Shows No Negative Impact on Horizontal Gene Transfer
February 15th 2024For this analysis, investigators used metagenomic sequencing files from the Gut Bugs trial, a placebo-controlled multidonor fecal microbiota transplantation (FMT) trial conducted among adolescents classified as obese.
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Registry Reveals Sex Differences in HoFH Diagnosis, Treatment, and Cardiovascular Outcomes
February 15th 2024Although the prevalence of myocardial infarction (MI) was doubled among men compared with women with homozygous familial hypercholesterolemia (HoFH), both sexes had similar ages at first MI.
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Cultural Influences, Surgical Decision-Making Approaches for Non-Caucasian Women With Breast Cancer
February 14th 2024Non-Caucasian patients with breast cancer face common influences in surgical decision-making due to fear, misinformation, cultural factors, and power dynamics, highlighting the need for patient-centered surgical decision-making.
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