Inotuzumab Ozogamicin Plus Dose-Adjusted EPOCH: Promise in R/R B-ALL
June 5th 2024Phase 1 trial results indicate that combining inotuzumab ozogamicin with dose-adjusted EPOCH chemotherapy could offer a safe, well-tolerated, and effective treatment option for patients with relapsed or refractory CD22+ B-cell acute lymphoblastic leukemia or lymphoma (R/R B-ALL).
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Antibody Drug Conjugates Show Promise in Biomarker, Prognostic Outcomes in Oncology Care
June 5th 2024Posters presented at ASCO 2024 found positive responses in the prediction of tumor types and prognostic outcomes in patients with advanced solid tumors and HR+/HER2-negative (HER2–) metastatic breast cancer.
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Prophylaxis With Recombinant ADAMTS13 Demonstrates Superiority vs Standard Therapy in Congenital TTP
June 5th 2024The multinational, open-label, controlled, randomized, crossover, phase 3 TAK-755 (NCT03393975) trial demonstrated superior efficacy and safety of recombinant ADAMTS13 as prophylaxis in patients with congenital thrombotic thrombocytopenic purpura (cTTP) compared with standard therapy.
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FDA advisers have voted against the use of MDMA as a post-traumatic stress disorder (PTSD) treatment; House members have expressed support for the 340B drug discount program but disagreed on whether it needs tighter regulation; a federal judge sided with SCAN Health Plan over CMS about incorrect 2024 Star Rating calculations.
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Equity in Motion at CMS Health Equity: Dr Aletha Maybank Shares AMA Advances for Justice
June 5th 2024Chief Health Equity Officer and Senior Vice President Aletha Maybank, MD, MPH, of the American Medical Association (AMA), delivered a powerful plenary session at the CMS Health Equity conference exploring the changes sparked by pivotal moments within the last 5 years.
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Same Hypertension, Different Levels of Portal Engagement, Disparities Research Shows
June 4th 2024When patients are treated in primary care for high blood pressure, sociodemographic factors sway the rates at which they access patient portals, investigators found. This could influence their hypertension outcomes.
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Gathering Data on Circadian Rhythms, Sleep in Adolescents Poses Challenges in Lab and Home Testing
June 4th 2024The session held at SLEEP 2024 focused on the challenges of collecting data on sleep and circadian rhythms in adolescents, as well as the difference between home and lab measurements.
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Mental Health Care Dominates Telehealth Visits, Study Finds
June 3rd 2024An analysis drawing on data from the 2021 Medical Expenditure Panel Survey (MEPS) highlights that a significant portion of telehealth visits were for mental health services despite the overall telehealth utilization being relatively low.
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TB Vaccine Shows Protection Against COVID-19 in People With T1D
June 3rd 2024In the course of investigating the use of Bacillus Calmette-Guérin for high-risk individuals who have type 1 diabetes (T1D), researchers hoped—and found—that BCG could substantially reduce the chance of those with T1D contracting COVID-19; BCG has historically been used to prevent tuberculosis (TB).
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Proof-of-Concept Study Highlights Potential of Gene-Based Therapy for Timothy Disease
June 2nd 2024The proof-of-concept study showed that antisense oligonucleotides developed by the researchers successfully restored cellular development and brain cell function in patients with the disease characterized by multiorgan dysfunction.
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