Jared Kaltwasser

Graft-versus-host disease (GVHD) is common, yet it is poorly understood and its symptoms can be difficult to recognize.

As noninvasive ventilation grows in popularity, new research examines when the therapy works, and when clinicians should be cautious.

The new study suggests certain sub-categories of patients are at particularly high risk.

The study points to the challenges of treating chronic obstructive pulmonary disease in a remote region in a country with a high smoking rate.

The patient had no obvious pulmonary symptoms, but a routine chest X-ray helped investigators arrive at the diagnosis.

The new research is aimed at a patient group often left out of research studies.

The new recommendations for systemic lupus erythematosus (SLE) use disease activity index scores and evaluator’s global assessment measures, but they do not include serology.

A new study comparing intensive care unit stays among patients with Parkinson disease and controls without the disease found the former have more severe illness, but both groups have similar survival rates.

A new study characterizes the rate of allergic contact dermatitis among patients given skin adhesives.

A new report finds patients with systemic lupus erythematosus and 5 other autoimmune disorders face an increased risk of gastric cancers.

A total of 92 gene variants were sequenced, 41 of which were novel.

The patient experienced lasting improvement when belimumab was added to her regimen after 2 years.

Women with systemic lupus erythematosus (SLE) were twice as likely to experience carotid plaque buildup during the 5 years of this study.

In a new review article, investigators outline the challenges to studying the disease, but also point to big data as an important tool moving forward.

Investigators found anti-ribosomal P protein antibodies, a serological marker for systemic lupus erythematosus (SLE), were linked with higher ferritin levels, independent of interleukin 6 levels.

Despite the increase in relapse risk, 2-year survival for patients with graft-versus-host disease (GVHD) who received matched sibling donor (MSD) allogeneic hematopoietic cell transplant (allo-HCT) administered post-transplant cyclophosphamide remained similar compared with patients receiving cyclosporine A with methotrexate prophylactically.

Patients who took supplements had improvements, although they did not become apparent until patients had been taking supplements for a year.

Children with uncontrolled asthma had a 3- to 6-times the risk of hospitalization for COVID-19, the investigators found.

Fifty-one therapies have been approved for rare neurological diseases since the FDA passed the Orphan Drug Act in 1983.

Patients with SLE had higher levels of Wnt5A if they were experiencing active disease.

A new case report highlights a patient who presented with seizure-like symptoms but was later diagnosed with the rare lysosomal storage disorder.

The trend was true when investigators used body mass index to classify weight, and when measures such as relative body mass index and percentage of body fat were used.

Clinicians should be willing to work with patients eager to try “do-it-yourself” insulin systems, but should also warn them of the risks, the guidelines state.

Dutch investigators found a screening questionnaire might be a good tool to identify patients warranting further testing for systemic lupus erythematosus (SLE).

Kidney organoids designed with the same mutation as that present in Fabry disease can help investigators better understand how the disease functions, authors suggested.

An open-label randomized trial found patients using the closed-loop system had more time in their target glucose ranges.

The study showed children with thalassemia had a greater risk of both atopic and non-atopic asthma.

Five gene hubs were identified, with one in particular appearing to correlate strongly with the pathogenesis of lupus nephritis.

The case required significant testing to get to the correct diagnosis, but the investigators hope their experience helps inform doctors facing similar cases in the future.

The report, based on a survey conducted in Spain, suggests patients are suffering from additional asthma exacerbations due to a lack of understanding of their disease.