Jared Kaltwasser

A patient’s quick response to cemiplimab (Libtayo) was reversed after the therapy was stopped due to progression of apparent metastatic cutaneous squamous cell carcinoma.

A dichotomous classification scheme has helped in the intrahepatic cholangiocarcinoma (iCCA) space, but some potential variants require further exploration, the article states.

Levels of the hormone increase with disease severity, a new study has found.

The study, based on a case series in Japan, found the risk of grade 2 or above chemoradiation increased when durvalumab was started within 14 days of the final thoracic radiotherapy treatment.

Investigators said the benefits appeared relatively early in treatment for many patients and persisted throughout the study period.

A single-center analysis of more than 30 years of data shows rates of preterm births and preeclampsia remained stable

The study suggests standardized uptake values may be a useful marker to predict treatment response and prognosis in lung adenocarcinoma.

The investigators cautioned, however, that the factors identified had only modest predictive power.

Physicians should consider measuring anti-endothelial cell antibodies in patients with polycythemia vera, the investigators suggested.

A systematic review and meta-analysis found no clear advantage for automated red cell exchange.

Study data are mixed, but some evidence suggests the administration of vitamin D may work as a low-risk prophylactic against graft-versus-host disease (GVHD).

Hepatobiliary-phase enhanced imaging outperformed diffusion-weighted imaging in distinguishing intrahepatic mass-forming cholangiocarcinoma, but the accuracy is greater when these methods are used in tandem.

A new model may be able to better identify which patients will respond to immunotherapy.

The study, based on 33 years of data, also explored auto-antibody production in the rare patient group.

Levels of the 2 markers appeared to indicate both the presence of SLE and disease activity levels.

Patients said they benefited from diabetes management technology, but also from social accountability.

Investigators also found patients in nursing homes tend to have larger tumors and may experience quality-of-life benefits from the procedure.

Prior to the pandemic, youth with sickle cell disease were more likely to report depressive symptoms, but the opposite was true during the pandemic.

A cure for sickle cell disease could more than double the lifetime incomes of patients, the study found.

Forty-two percent of patients in the cohort had an adverse pregnancy outcome.

The analysis suggests the marker could be used to screen patients for potential immunotherapy.

Body mass index did not appear to correlate with glycemic control, the study found.

Patients with higher levels of interferon-β (IFNβ) in their B cells were less likely to have oral and nasal ulcers or photosensitivity.

A panel of experts suggests adding caplacizumab to the historic treatment of plasma exchange and immunosuppression could lead to significant improvement in outcomes for patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP).

The study suggests blood pressure and cholesterol medications may be appropriate for some younger patients in order to prevent renal complications.

The findings could lead to new insights into how type 1 diabetes develops.

Patients of Asian heritage were also more likely to have end-organ manifestation, the authors found.

The microenvironment of the skin also helps explain why certain ethnicities appear to have a higher risk of melanoma.

In some cases, however, the rate of decline is no different than that of the general population, according to new research.

The pain, planning, emotional health, and fatigue quality of life domains were most impacted as a result of severe systemic lupus erythematosus (SLE) flares.