Jared Kaltwasser

Acid sphingomyelinase deficiency (ASMD) is a rare lysosomal storage disorder; a new report said that plasma lyso-sphingomyelin levels can be used to not only diagnose the rare disease but also predict severity and type.

A new study suggests the lower-cost, more patient-friendly assessment method may be a useful tool for clinicians.

This new study adds to the literature by giving the first long-term data in these populations.

When patients are quickly readmitted, they have higher health care costs, a new study has found.

A look at the existing literature suggests more questions than answers remain when it comes to the potential use of the cholinergic anti-inflammatory pathway in connective tissue diseases (CTDs).

A minority of patients will experience flares, but in most cases reintroduction of therapy will result in remission.

The reports suggest patients with rheumatoid arthritis (RA) could experience secondary neurological adverse events, though the side effect appears to be rare.

Intravenous belimumab had benefits, but also resulted in more health care utilization due to the nature of its administration.

Advanced dementia and serum albumin levels were better predictors of poor outcomes, the investigators said, among older patients with Clostridioides difficile infection (CDI).

A new report shows patient readmissions and mortality dropped among patients aged 65 and older following the institution of an antibiotic stewardship program.

Patients with rheumatoid arthritis (RA) who used tumor necrosis factor (TNF) inhibitors had significantly higher rates of nonmelanoma skin cancer and non-Hodgkin lymphoma.

Treat-to-target has long been used in adults, but a new study finds it is warranted in pediatric cases, too.

Five case reports suggested the anti-BAFF monoclonal antibody was effective at reducing disease activity scores for adults who have neuropsychiatric systemic lupus erythematosus (NPSLE).

A new study lends insights into the prevalence of lung abnormalities in patients with newly diagnosed cases of rheumatoid arthritis (RA).

This new analysis of combination treatment with ipilimumab and nivolumab identified factors likely to lead to therapeutic success with the combination.

In pediatric patients with frequently relapsing nephrotic syndrome (FRNS), the therapy was well tolerated, but did not lead to significant changes in disease course.

Patients with BRAF-V600 mutated metastatic melanoma have new treatment options to consider, but scientists are still waiting on additional data to help choose which first-line treatments are best for which patients.

Patients over the age of 65 had similar rates of serious adverse events, and nearly identical progression-free survival, when compared with younger patients.

A review of cases using MRI with and without contrast agent found perfect or near-perfect agreement in most cases when evaluating patients with short stature for growth hormone deficiency.

The new study, based on an analysis of existing literature and a replication cohort, helps clarify the role of a variant in microRNA-146a.

By year 5 of therapy with disease-modifying anti-rheumatic drugs (DMARDs), only about one-third of patients with psoriatic arthritis (PsA) were expected to be continuing with their therapy.

People who suffered trauma as a child appear to be at a higher risk of fibromyalgia, although it is unclear exactly why.

Patients with systemic lupus erythematosus (SLE) said they still suffered significant pain and fatigue, even though they reported high rates of satisfaction with their therapies.

This new analysis aimed to pinpoint more rigorous predictors of mortality, and it was able to identify “excellent” but not “outstanding” ones, according to the investigators.

Autophagy inhibition could help patients who develop resistance to BRAF inhibitors, but a new review shows important questions remain.

Randomized controlled trials on asthma hospitalization prevention are limited, but patient and caregiver education should be a top priority, investigators said.

A new report suggests corticosteroids likely are not a panacea for ocular surface disease, a potential adverse effect of trabeculectomy.

Patients with axial spondyloarthritis waited the longest, according to new research.

Among patients who suffer an in-hospital cardiac arrest, acute kidney injury (AKI) raised the risk of all-cause in-hospital mortality from about 30% to more than 60%.

A new mathematical model highlights the challenges of preventing Clostridioides difficile transmission in the hospital.