Social Determinants to AML Treatment Approach

EP: 1.Overview of Pathophysiology of and Progression of AML

EP: 2.Risk Classification Systems in AML

EP: 3.Key Patient Factors to Consider in AML Treatment Decisions

EP: 4.Provider Perspectives on Biggest Unmet Needs in AML Care

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EP: 5.Social Determinants to AML Treatment Approach

EP: 6.Latest NCCN Guidelines on the Standard of Care for Patients With AML

Patients with acute myeloid leukemia (AML) face unique challenges related to social determinants of health that significantly impact their treatment access and outcomes. Geographic distance from specialized treatment centers creates substantial barriers, as patients require frequent monitoring, blood transfusions, and urgent medical attention throughout their treatment course. Unlike solid tumor patients who might visit clinic every few weeks, AML patients often need care multiple times weekly, making transportation and proximity to treatment facilities critical factors in treatment success.

The intensive nature of AML care creates particular hardships for patients with limited social support, inadequate housing, or financial constraints. Patients must navigate complex treatment regimens while managing the physical and emotional stress of a life-threatening diagnosis, often becoming primary caregivers’ full-time responsibility. The immunocompromised state that results from both the disease and its treatment requires patients to limit social interactions and maintain strict infection precautions, leading to isolation that can significantly impact mental health and treatment adherence.

Health care teams increasingly recognize that addressing social determinants requires comprehensive support beyond medical treatment alone. Patients benefit from early integration of palliative care services to help manage symptoms, reduce anxiety, and improve quality of life throughout the treatment journey. Sexual health concerns, while understudied in leukemia patients, represent an important quality of life issue that deserves attention and support. Successful AML care requires coordinated efforts to address transportation barriers, provide psychosocial support, ensure adequate nutrition, and maintain patients’ connection to their support systems while managing the demands of intensive treatment protocols.