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Role of Pharmacy Benefit Managers in Oncology

Opinion
Video

Panelists discuss how PBMs shape oncology access and stress the need for transparency to align financial control with clinical priorities.

Panelists discuss how pharmacy benefit managers (PBMs) play a growing role in determining oncology access and affordability. They explain that PBMs increasingly influence formulary design, rebate negotiations, and drug-tier placement, impacting both providers and patients. While PBMs can help control costs, panelists caution that opaque rebate structures sometimes distort clinical priorities, favoring cost-driven rather than evidence-driven decisions.

They highlight how PBMs’ influence extends to treatment sequencing, prior authorization, and preferred drug lists. This consolidation of control can streamline some processes but also limit flexibility for oncologists to tailor regimens based on patient needs. Transparency and stakeholder collaboration are recurring themes, as participants call for clearer justification of formulary exclusions and step edits.

Ultimately, the discussion underscores the need for greater alignment between PBM strategies, clinical data, and patient outcomes to ensure that financial mechanisms support—rather than impede—quality oncology care.

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