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Overcoming Immunotherapy Resistance: Identifying Non-Responders and Novel Approaches
The panel shares clinical practices for overcoming immunotherapy resistance in patients with non-small cell lung cancer.
EP: 1.Biomarker Testing and Guideline-Recommended Care in mNSCLC
EP: 2.Strategies to Increase Biomarker Testing Rates
EP: 3.Limitations on Optimal Biomarker Testing Rates
EP: 4.Impact of Biomarker Testing on Treatment Selection and Outcomes
EP: 5.Key Challenges and Unmet Needs in Newly Diagnosed Driver-Negative mNSCLC
EP: 6.NCCN Recommendations by PD-L1 Expression Level
EP: 7.Limitations of NCCN PD-L1 Expression Recommendations
EP: 8.Emerging Data and Evidence for Dual Immunotherapy plus Chemotherapy in First-Line mNSCLC
EP: 9.Genetic Alterations Impacting Treatment Response and Biomarker Testing Rates in mNSCLC
EP: 10.Molecular Characteristics Beyond Mutations Influencing Immunotherapy Response
EP: 11.Clinical Factors Impacting Immunotherapy Response and Optimizing Patient Selection
EP: 12.Overcoming Immunotherapy Resistance: Identifying Non-Responders and Novel Approaches
EP: 13.Key Takeaways on Enhancing Outcomes for mNSCLC Without Targetable Driver Mutations
Video content above is prompted by the following questions:
- What gaps remain in identifying likely non-responders to immunotherapy to guide alternative treatments?
- How does the toxicity profile of immuno-oncology regimens compare to standard chemotherapy options?
- Are there ongoing trials or research on novel combination approaches to overcome resistance and improve immunotherapy efficacy?
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December 23rd 2024Ryan Nguyen, DO, physician and researcher at the University of Illinois Chicago, emphasizes the transformative impact of immunotherapy in non–small cell lung cancer (NSCLC) and the need for precise biomarkers and equitable access to advanced treatments through systemic testing protocols.
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