April 3rd 2025
Several studies have been conducted, but questions remain about where such therapies will fit into multiple myeloma treatment strategies.
Review Highlights Knowledge Gaps in Lymphoma Treatment Outcomes in AYAs
September 7th 2023The review summarized existing evidence around short- and long-term treatment-related toxicities among adolescents and young adults (AYAs), as well as gaps in care guidelines for AYA survivors of lymphoma.
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Standard Uptake Value Index May Aid in Diagnosis of Polymyalgia Rheumatica
August 8th 2023Polymyalgia rheumatica (PMR) is an inflammatory disease often misdiagnosed as certain cancers, among other diseases. Researchers have recently made progress to better diagnose PMR using a standard uptake value index based on fluorodeoxyglucose with positron-emission tomography/computed tomography.
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ASCO 2023: Leukemia and Lymphoma
July 31st 2023Results include a landmark study that involved seamless collaboration across adult and pediatric patient groups, leading to a highly diverse study population. Other coverage addresses access to novel therapies and what's coming in the pipeline, including CAR T-cell therapy with tyrosine kinase inhibitors.
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Cell Protein GRP78 Affects Cancer Cell Spread, USC Study Reveals
July 25th 2023New research suggests that when cancer cells are under stress, cellular chaperone protein GRP78 alters its behavior and migrates to the cell's nucleus, where it modifies gene activities and allows cancer cells to become more mobile and invasive.
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Dr Byron Lam Reviews Current Treatments and Therapies in the Pipeline for Inherited Retinal Disease
June 11th 2023The most exciting treatment for inherited retinal disease was approved in 2017, but there are many novel treatments in phase 2 or phase 3 trials at this point, said Byron L. Lam, MD, professor of ophthalmology, University of Miami Miller School of Medicine's Bascom Palmer Eye Institute.
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The successful collaboration between a primary care–based network of practices and academic researchers demonstrates feasibility and the need for more funding for primary care research.
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Dr Byron Lam Discusses Impact on SES Factors on Glaucoma Screening Follow-up
May 29th 2023Insurance is by far the most important factor of whether patients followed up with treatment after getting screened for glaucoma, said Byron L. Lam, MD, professor of ophthalmology, University of Miami Miller School of Medicine's Bascom Palmer Eye Institute.
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Characteristics of Relapse Affect Treatment Choices in Multiple Myeloma
April 3rd 2023Natalie S. Callander, MD, director of the University of Wisconsin Carbone Cancer Center Myeloma Clinical Program, reviewed the treatment landscape at the National Comprehensive Cancer Network (NCCN) 2023 Annual Conference.
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Dr Eva Parker: Climate Change Has Been Impacting Skin Diseases for Years
March 17th 2023Many people often don’t connect the dots between climate change and its impact on skin health, but these effects have been happening for years, said Eva R. Parker, MD, associate professor of dermatology at Vanderbilt University Medical Center.
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Study of South African Males With Prostate Cancer Reveals Limits of Current Germline Testing
March 10th 2023The findings, published in the Journal of the National Comprehensive Cancer Network, add to the evidence that the shift to precision medicine is built on data that have not included sufficient numbers of patients of color.
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42 Health Systems Picked for PCORI Plan to Move Clinical Research to Practice
March 3rd 2023Seeking to speed up the execution of evidence-based care practices, the Patient-Centered Outcomes Research Institute (PCORI) announced the 42 health systems across the country who will join a 5-year program to build capacity and implementation to improve health care outcomes.
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BRVO, CRVO Need More Effective Long-term Therapies
February 12th 2023While the current therapies are effective for treating branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO), they are inadequate for long-term treatment in clinical practice, according to an analysis of real-world data.
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High-Dose Aflibercept in Wet AMD and DME Provides Therapeutic Benefits, No New Safety Signals
February 12th 2023Two studies looking at a higher dose of aflibercept found that an 8-mg dose can be maintained at longer dosing intervals with similar benefits and no additional safety signals compared with the 2-mg dose.
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Home OCT: Providing More Personalized, Timely Treatment for Wet AMD
February 11th 2023Home optical coherence tomography (OCT) has shown there is a wide degree of heterogeneity in fluid dynamics and treatment response that may not be clear during regular office visits and scans. Presenters reviewed the latest data in home OCT to manage wet age-related macular degeneration (AMD).
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Mitochondrial Stabilizing Drugs Have Potential to Reverse Vision Loss in Dry AMD
February 10th 2023A review of data on 2 mitochondrial membrane stabilizers—risuteganib and elamipretide—has highlighted the potential to not just slow disease progression but actually reverse vision loss in patients with intermediate dry age-related macular degeneration (AMD).
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Improved Implementation Strategies Can Further Advance SMA Care, Researchers Say
January 7th 2023The diagnosis and treatment of a rare disease like spinal muscular atrophy (SMA) would benefit greatly from using implementation science to reduce the variation that exists in screening and therapy, according to researchers.
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Individual clinicians can lead efforts to build trust in science and distribute accurate information, but medical schools also have an important role to play in training health care professionals to communicate with the public, according to Vineet Arora, MD, MAPP, dean for medical education at UChicago Medicine.
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Flight Home From Pharmacy Conference Holds More Surprises With Medical Emergency
December 9th 2022As they headed home Thursday from the 2022 American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting & Exhibition in Las Vegas, pharmacists pitched in to help a man having a medical emergency aboard a United flight bound for Newark, New Jersey.
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