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Over the 24-year period, there were 57 spinal muscular atrophy diagnoses in 53 families, and a disease birth prevalence of 1 per 8286 births in Estonia.

Throughout their paper, researchers highlighted acne treatment for these patients often involves other considerations—including reproductive health and mental health—and dermatologists should keep these in mind when making decisions for each patient.

Given the heterogeneous nature of breast cancer, biomarkers evaluated throughout treatment help provide a clearer picture of the treatment paradigm.

Patients with atopic dermatitis were associated with significant economic burden primarily driven by outpatient visits and pharmacy use, which increased with disease severity.

Unvaccinated older adults are 49 times more likely to be hospitalized after contracting COVID-19; nursing homes are experiencing a major staffing crisis; major Alzheimer groups plan to meet with federal officials and lawmakers to protest the CMS drug proposal.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

For the first time, a major study showed that remission for peanut allergy can be achieved even in very young children using oral immunotherapy.

More nutritional care may be needed for elderly patients with chronic kidney disease (CKD) who are ingesting higher-than-recommended amounts of protein, investigators concluded.

Recent research suggests targeted memory reactivation might help with facial recognition and name recall, but quality and quantity of sleep may be important factors in effectiveness.

The frequency of several mutations that inhibit response to tyrosine kinase inhibitors and tend to lead to increased disease severity was elevated in Chinese patients with non-small cell lung cancer.

Results of a study conducted among Finnish migraineurs highlight a link between the condition and hypertension.

In a small study, evidence suggested 8-Hydroxy-2'-deoxyguanosine levels negatively correlated with a test of exercise endurance.

Drug makers sign on to help produce Merck’s COVID-19 pill for developing countries; research shows promise for organ transplants from genetically modified pigs; blood sample collection tubes added to FDA list of shortages.

Patients whose endurance increases will likely have a higher quality of life and ability to carry out daily functions, the authors said.

On this episode of Managed Care Cast, we interview the lead author of a paper in the Health IT issue of The American Journal of Managed Care.

Zanubrutinib is a second-generation Bruton tyrosine kinase (BTK) inhibitor that has fewer off-target effects and less cardiotoxicity than ibrutinib, a first-generation BTK inhibitor.

These new study findings support a link between faster walking pace and reduced risk of developing heart failure and its subtypes.

Implementing evidence-based guidelines (EBGs) resulted in a 17.3% reduction in anaphylaxis-related hospitalizations among children.

The data published in Scientific Reports are the first to implicate a role for RASGRP4 mutations in B-cell malignancies.

The trastuzumab biosimilar Herzuma was shown to have similar clinical efficacy and safety to the reference product in patients with HER2-positive advanced gastric cancer.

Patients with severe chronic rhinosinusitis with nasal polyps achieved significant improvements in health-related quality of life (HRQOL) and general health status with dupilumab treatment after 52 weeks.

A model developed by researchers in China could help identify patients with non–small cell lung cancer (NSCLC) most likely to benefit from anti– programmed death-ligand 1 (PD-L1) immunotherapy.

Findings of a pilot study suggest that gut microbiome differences resulting from environmental factors could affect racial disparities in type 2 diabetes.

An analysis conducted in Japan among patients with acute decompensated heart failure (HF) revealed excessive polypharmacy at hospital discharge is associated with an increased risk of mortality after 1 year.

Incidence of infectious diseases, skin infections, and systemic antibiotic exposure were all associated with the development of atopic dermatitis among infants and young children.

Research presented at the 2021 American Society of Hematology Annual Meeting and Exposition highlights efforts in screening for multiple myeloma (MM).

A study comparing 4 different artificial intelligence (AI) models found that some models were better than others at detecting early-stage chronic kidney disease (CKD), when patients do not experience visible symptoms.

The Biden administration will distribute 400 million nonsurgical N95 masks; a study aims to develop a questionnaire to enable gay and bisexual men to donate blood; counterfeit versions of Gilead HIV treatments were discovered in 9 states.

Patients with psoriatic disease and dermatologists reported their preferred strategies to improve cardiovascular disease risk management, with a specialist-led model of care touted by both groups.