Real-world Study Identifies Several Predictors of Risankizumab Response in Psoriasis
February 14th 2022Risankizumab was shown to be highly effective in patients with moderate to severe psoriasis of tertiary medical centers in Italy, in which response was found to be significantly affected by smoking, and incidence of psoriatic arthritis.
Read More
What We're Reading: COVID-19 Vaccine Expansion Halted; PBM Probe; High-Volume Antibiotic Prescribers
February 14th 2022The FDA delays its decision on Pfizer/BioNTech’s COVID-19 vaccine in young children; the Federal Trade Commission (FTC) will vote on whether to investigate pharmacy benefit managers (PBMs); nearly half of high-volume antibiotic prescribers are located in Southern states.
Read More
A statement from NCCN’s Advisory Committee on COVID-19 Vaccination and Pre-exposure Prophylaxis said that the panel “endorses vaccination for all eligible persons based on FDA-approved indications or emergency use authorization” and emphasized the need for everyone to be fully vaccinated—including third doses.
Read More
Researchers Offer Comprehensive Look at Rosacea Treatment Options
February 12th 2022Affecting up to 1 in 10 people worldwide, rosacea has a complex pathophysiology that remains inadequately understood, and research has hinted at multiple inflammatory and immune mediated processes underlying the condition.
Read More
Researchers Determine What Patients, Caregivers Deem Meaningful Change in SMA Motor Function
February 12th 2022Through the use of patient testimonials as well as analysis of data from a study of patients with spinal muscular atrophy (SMA), researchers were able to describe patient-centered “meaningful outcomes” in the 32-item Motor Function Measure.
Read More
Early Response to Biologics Linked With Stable Long-term Efficacy in Psoriasis
February 12th 2022More patients with moderate-to-severe psoriasis were found to be early responders to ixekizumab vs ustekinumab; all those who achieved early response were associated with stable skin clearance long-term.
Read More
Exercise Interventions Benefit Patients With Asthma, Review Shows
February 12th 2022While it is known that the promotion of physical activity can improve asthma symptoms and quality of life—and is even recommended in asthma guidelines— such behavior change is often difficult due to lack of funding or reimbursement for pulmonary rehabilitation or for other reasons.
Read More
More Info Needed to Establish Utility of MRD, SFLC Levels as Biomarkers in MM
February 12th 2022This new study synthesized data from 5 clinical trials at the University of California, San Francisco, to evaluate the utility of minimal residual disease (MRD) and serum-free light chain (SFLC) levels in predicting progression-free survival among patients with multiple myeloma (MM) receiving chimeric antigen receptor T-cell therapies.
Read More
IO-TKI Combinations Have Potential as Preferred First-line mRCC Therapy
February 12th 2022Metastatic renal cell carcinoma (mRCC) has seen increased treatment options in recent years, including immunotherapy (IO) combinations paired with tyrosine kinase inhibitors (TKI). A meta-analysis of phase 3 trials aimed to compare and rank available first-line treatments.
Read More
Switching to Dry Powder Asthma Inhaler Better for Climate Change, Researchers Say
February 11th 2022Researchers in the United Kingdom compared the potential impact on carbon footprint and asthma symptom control of switching maintenance therapy to a dry powder inhaler vs continuing with a metered dose inhaler containing hydrofluorocarbon propellant.
Read More