CAR T-Cell Therapy Outcomes Are Not Impacted by Baseline Renal Function, Study Finds
September 30th 2022Renal outcomes and chimeric antigen receptor (CAR) T-cell therapy efficacy were unaffected by baseline renal status in a cohort of patients with diffuse large B cell lymphoma, but acute kidney injury during treatment was associated with worse clinical outcomes.
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What We’re Reading: FDA Approves ALS Drug; Role of Microbes in Tumors; Suicides Increased in 2021
September 30th 2022The FDA approved AMX0035 (Relyvrio) for amyotrophic lateral sclerosis (ALS) Thursday; new research suggests looking at microbes and fungi within cancer tumors; US suicides increased in 2021 following a 2-year decrease in deaths by suicide.
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Contributor: It’s Time to Talk About Paying Clinical Trial Participants More
September 30th 2022There is wide variation in the governance over research participant pay, and with rapid advances in technology enabling trial access, industry should step up and pay patients what they are worth, says Gunnar Esiason, a patient advocate living with cystic fibrosis.
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What We’re Reading: Teen Substance Use Trends; Physician Burnout Increasing; Employee Mental Health
September 29th 2022Alcohol and cigarette use among teens declined between 1991 and 2019, while vape use increased; most US physicians reported at least 1 symptom of burnout between the end of 2021 and beginning of 2022; an estimated 12 billion annual workdays are lost due to depression and anxiety among employees.
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CDC to Physicians: Watch for Severe Respiratory, Polio-Like Illness in Children
September 28th 2022The CDC this week noted what providers and parents have been seeing across the country: rising cases of a non-polio enterovirus causing severe respiratory illness and acute flaccid myelitis (AFM).
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Pediatric ESS Effective, Safe to Treat Chronic Sinusitis With Nasal Polyps
September 28th 2022With a high recurrence rate following surgery to treat chronic sinusitis with nasal polyps, authors set out to investigate the effectiveness and safety of endoscopic sinus surgery (ESS) in a pediatric patient population.
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FDA Committee Issues Positive Vote for RBX2660 in Recurrent Clostridioides difficile Infection
September 28th 2022An FDA advisory committee recently issued a positive vote for Ferring’s RBX2660, an investigational microbiota-based live biotherapeutic, for its potential in reducing recurrent Clostridioides difficile infection after antibiotic treatment.
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Potential for PHC Necessitates Pediatric Cardiology Care for Children With PAH
September 28th 2022Outcomes following right heart catheterization in a pediatric patient population were analyzed, with emphasis placed on risk of adverse outcomes following the procedure, especially the development of pulmonary hypertensive crisis (PHC).
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Square-Stepping Exercise Linked With Improved Executive Functioning in Parkinson Disease
September 28th 2022Adherence to 8-week square-stepping exercise training among patients with Parkinson disease was associated with significant improvement of executive functioning, as well as cognitive functioning for those with mild cognitive impairment.
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FAIR Health Releases Report on Substance Use Disorders, Overdoses Before, During Pandemic
September 27th 2022One of the key findings of the report is that 42 states saw an increase in the proportion of patients with opioid and opioid-like drug overdoses compared with the total number of patients using medical services by state.
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Clostridioides difficile Infection Risk Greater Among Patients Requiring Maintenance Hemodialysis
September 27th 2022Patients requiring maintenance hemodialysis (MHD) had a 4-fold higher risk of Clostridioides difficile infection (CDI), with rates of CDI increasing over time regardless of MHD requirement.
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Biogen Inc agreed to pay $900 million to settle allegations about improper physician payments; the American Cancer Society warns that fertility preservation for patients with cancer is at risk after the overturn of Roe v Wade; the Supreme Court will hear a case about Medicaid recipients’ ability to sue their providers.
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