Researchers Develop Prognostic Model for Survival in Patients With MF Undergoing Allo-HCT
May 8th 2023In addition to current available risk scores, the new system can help counsel patients with myelofibrosis (MF) undergoing allogeneic hematopoietic stem cell transplantation (allo-HCT), authors wrote.
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Study: Adding GLP1RA to T2D Therapy Linked With Lower MACE In Older Patients Without CVD
May 8th 2023Study authors said the findings could inform clinicians when selecting therapies for patients with type 2 diabetes (T2D). However, an editorial found the follow-up period too short and differences between the study arms too small to be meaningful.
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Dr Fran Gregory Discusses the Impact of the New Wave of Biosimilars on Rebate Practices
May 8th 2023Fran Gregory, PharmD, vice president of emerging therapies at Cardinal Health, discusses the role the new wave of biosimilars will have on rebate practices for both pharmacy benefit managers (PBMs) and payers.
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Dr Mark Fendrick Discusses How the Braidwood Ruling Could Affect Cost-Sharing
May 8th 2023Cost sharing for several treatments could disappear following the Braidwood v Becerra ruling, according to A. Mark Fendrick, MD, director of the V-BID Center at the University of Michigan and co-editor in chief of The American Journal of Managed Care®.
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Addressing Unmet Need: Could Children With Low-Grade Gliomas Have a New Treatment in Tovorafenib?
May 6th 2023For Brain Cancer Awareness Month, AJMC shares an interview with Day One Biopharmaceuticals CEO Jeremy Bender, PhD, MBA. Bender discussed the company's lead agent, tovorafenib, which has shown promise in treatment of pediatric low-grade glioma.
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Youth Diabetes Risk Perception Not Associated With Engagement in Risk-Reducing Behaviors
May 5th 2023Diabetes risk perception was linked to increased TV watching and 1 less day per week of at least 60 minutes of exercise, and was not associated with nutrition or weight loss attempts among adolescents.
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Certain Comorbidities May Predict Cardiovascular Event Risk After ADT for Prostate Cancer
May 5th 2023The presence of certain comorbidities prior to androgen deprivation therapy (ADT) for prostate cancer may be associated with a greater risk of cardiovascular events after starting ADT, recent research found.
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Patients With Advanced Cancer With High TMB Show Favorable Outcomes on ICIs
May 5th 2023A recent study found that patients with advanced solid cancers with high tumor mutational burden (TMB) saw improved outcomes on immune checkpoint inhibitors (ICIs) compared with patients who had low-TMB cancers.
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Despite Concerns Over Extrapolation, Bevacizumab Biosimilars Are Widely Used in mCRC
May 5th 2023A review article investigating the use of bevacizumab biosimilars found that despite lingering concerns about their usage for extrapolated indications, bevacizumab biosimilars are regularly used in metastatic colorectal cancer (mCRC) even though clinical tests only evaluate them in patients with lung cancer.
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The Biden administration has come to an agreement with the Alabama Department of Public Health to improve sewer services for residents of Lowndes County who have lived with pools of raw sewage; COVID-19 was still a leading cause of death in 2022; Medicare improperly paid providers for some psychotherapy services during the first year of the COVID-19 public health emergency.
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Research Explores Causes Behind Ineffective NO Treatment for Hypoxic Pulmonary Hypertension
May 5th 2023Researchers set out to examine the effects of sodium nitroprusside on the thromboxane-mediated contraction and nitric oxide (NO)-independent relaxation pathways and on reactive oxygen species accumulation in pulmonary artery smooth muscle cells.
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