Uncertainty, Coping Strategies Common Among Patients With AML, High-Risk MDS
February 2nd 2024Patients with comorbid acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) expressed a desire to discuss treatment options and maintain normalcy; they were not willing to have conversations involving their prognosis and future.
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Hospitalization, ER, and Medication Discontinuation Rates Still High in PNH
February 2nd 2024A retrospective analysis surveys the treatment landscape and patterns of patients with paroxysmal nocturnal hemoglobinuria (PNH), illuminating high hospitalization rates and emergency department use despite the availability of multiple treatment options.
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Evidence Linking Sleep to Improved Lower Back Pain Outcomes Is Weak, More Studies Needed
February 2nd 2024A systematic review of randomized controlled trials and prospective cohort studies concludes that sleep could be a prognostic component of lower back pain, but better evidence is needed.
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Pandemic-era policies that made it easier for patients to receive opioid addiction treatment will continue permanently; the Biden administration is facing pressure from Democrats and reproductive health groups to make sure the first OTC birth control pill is affordable; a FDA expert panel on Friday is set to resume the debate over how to make pulse oximeters more accurate for people with darker skin.
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Depression in Heart Failure: Data Support Psychotherapy or Medication Intervention
February 1st 2024The findings not only underscore the efficacy of 2 major interventions—Behavioral Activation Psychotherapy (BA) and Antidepressant Medication Management (MEDS)—but also support patient autonomy in choosing their preferred path to mental well-being.
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Bevey Miner: Unpacking the 21st Century Cures Act, the Role of Open Comment Periods
February 1st 2024Bevey Miner, executive vice president of health care strategy and policy, Consensus Cloud Solutions, discusses the complex landscape of proposed health care rules, and the potential impact of CMS' Advancing Interoperability and Prior Authorizations Rule.
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Further Studies Required as MS DMT Exposure During Pregnancy Increases
February 1st 2024A large-scale, population-based study examined patterns of disease-modifying therapy (DMT) exposure in pregnant patients with MS since 2010, revealing increased occurrences and the need for future studies to examine the impact of newer-developed DMTs.
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Telehealth, e-Health Psychological Interventions Potentially Promote Sexual Health in CRC
February 1st 2024Patients with colorectal cancer (CRC) could participate in telehealth and e-health interventions to promote their sexual health, although efficacy of these interventions needs to be further studied.
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Review: COVID-19 Pandemic Impact on Clinical Outcomes in Patients With Diabetes
February 1st 2024This systematic review found COVID-19 disruptions on clinical outcomes in those with diabetes to be more pronounced for females, younger people, and those a part of racial and ethnic minority groups.
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Older Adults in Traditional Medicare Spend Weeks Per Year on Health Care Contact Days
February 1st 2024Days spent obtaining health care outside the home may show access to needed care, but also add up to substantial time, effort, and cost burdens to patients and those who care for them, according to the study authors.
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CMS released the proposed 2025 Advance Notice for the Medicare Advantage (MA) and Medicare Part D Prescription Drug Programs; there have been 561 deaths related to the use of Philips’ recalled ventilators and machines for treating obstructive sleep apnea since 2021; the FDA warned the public against copycat eye drops due to infection risk.
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40-GEP Test Utilization Can Mitigate Financial Burden of Cutaneous Squamous Cell Carcinoma
February 1st 2024Medicare-eligible patients with cutaneous squamous cell carcinoma (cSCC) could save on health care costs by utilizing the 40-gene expression profile (40-GEP) to guide treatment decisions.
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Translating DMD Clinical Trial Findings to Real-World Application Discouraging
January 31st 2024This analysis compared outcomes among patients who have Duchenne muscular dystrophy (DMD) and commercial insurance or Medicaid, focusing on how these differ between patients in clinical trials and those who receive treatment post approval.
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Drug Prices and OOP Costs Increased Beyond Inflation Rates 2009-2018, But Were Not Related
January 31st 2024Drug prices in the US increased 4.4% annually and median out-of-pocket (OOP) costs increased 9.6% annually from 2009 to 2018, but there was no direct link between these amounts for individual drugs.
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What We’re Reading: Sickle Cell Treatment Access; Patent Thicket Attacks; US Syphilis Cases Rise
January 31st 2024Sickle cell disease (SCD) will be the first focus of the Cell and Gene Therapy (CGT) Access Model; the FTC has challenged the validity of over 100 drug product patents to help increase competition and potentially lower prices; the rate of infectious syphilis cases in the US rose 9% in 2022.
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Familial Hypercholesterolemia May Double Coronary Heart Disease Risk in Moderately Elevated LDL-C
January 31st 2024However, the association between familial hypercholesterolemia variants and coronary heart disease slightly weakened after adjusting for baseline low-density lipoprotein cholesterol (LDL-C) level and became statistically insignificant after adjusting for cumulative past LDL-C exposure.
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IV Methylprednisolone, Tacrolimus Effective in Prednisone-Resistant Ocular MG
January 31st 2024Researchers have retrospectively analyzed data from nearly 60 patients with ocular myasthenia gravis (MG) not adequately responding to oral prednisone, finding that both intravenous (IV) methylprednisolone and tacrolimus monotherapy helped reduce symptoms.
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