Type 1 Diabetes

A deal was reached to renew 5-year FDA user fee programs; children and adolescents with COVID-19 had a 60% increased risk of developing type 1 diabetes (T1D); states cannot penalize Department of Veterans Affairs (VA) employees for facilitating abortions permitted by federal law.

Children and adolescents with type 1 diabetes (T1D) saw improved quality of life (QOL) and metabolic control when using an advanced hybrid closed-loop (AHCL) insulin delivery method vs conventional therapy.

Treating children with mild diabetic ketoacidosis (DKA) using subcutaneous (SC) insulin aspart was linked to lower hospital costs and better efficacy of DKA management, compared with using intravenous (IV) insulin.

Women with type 1 diabetes (T1D) had a better cardiometabolic risk factor profile but did not have a significantly lower cardiovascular disease (CVD) event burden compared with their male counterparts.

A narrative review found that some risk factors may be associated with cognitive impairment in patients with type 1 diabetes.

People with type 1 diabetes (T1D) who partake in fasting during Ramadan may benefit from using an advanced hybrid closed loop (AHCL) insulin pump system.

The next step for health care professionals is to teach patients how to act on the data collected by intermittently scanned glucose sensing technologies, according to Viral Shah, MD, an endocrinologist and scientist.

A recent review examined to what extent childhood obesity increases the risk of various autoimmune diseases in adulthood, including type 1 diabetes (T1D), and the benefits that accrue if weight reduction begins in early life.

A study found cystatin C, renal resistance index, and urinary kidney injury molecule-1 were significantly associated with risk of diabetic kidney disease (DKD) in children and adolescents with type 1 diabetes (T1D).

Researchers achieved successful reactivation of pancreatic stem cells to become insulin expressing, suggesting future potential for replacing destroyed beta cells in patients with type 1 diabetes with newborn insulin-generating cells.

More efforts need to be made to remove unconscious bias when implementing approved diabetes technologies into clinical practice for all patients, said Viral Shah, MD, an endocrinologist and scientist.

The National Health Service (NHS) in England has made the Dexcom ONE real-time Continuous Glucose Monitoring System available by prescription to patients with type 1 diabetes (T1D).

Compared with sensor-augmented pump therapy, closed-loop insulin delivery increased glucose time in range and reduced hypoglycemia episodes but detracted from sleep quality.

While therapies for type 1 diabetes (T1D) are becoming more advanced, the problem is patients can't access them, said Viral Shah, MD, an endocrinologist and scientist.

Viral Shah, MD, an endocrinologist and scientist, discusses ongoing research on preventing bone fractures in people with type 1 diabetes (T1D).

Probability of continuous glucose monitoring device use was highest for patients with type 1 diabetes (T1D) in middle adulthood, decreasing as older age increased.

Viral Shah, MD, an endocrinologist and scientist, discusses his research on fracture risk assessment without bone mineral density as a predictor of major fractures in patients with type 1 diabetes (T1D).

Current guidelines recommend screening for the 2 most commonly diagnosed autoimmune diseases among adolescent patients with type 1 diabetes, but researchers suggest that additional screenings could benefit patients.

Screening for islet autoantibodies at ages 2 and 6 was highly predictive of type 1 diabetes (T1D) onset by age 15.

Patients, parents, and diabetes health care providers all play a role in ensuring children with type 1 diabetes (T1D) get adequate sleep, said Stacey Simon, PhD, sleep psychologist and associate professor, University of Colorado Denver, Children's Hospital Colorado.

Although the autoimmune response that reduces β cell numbers has often been the focus of research in type 1 diabetes (T1D), findings from a new study suggest proinflammatory signaling in islet β cells may play a significant role in disease progression.

Viral Shah, MD, an endocrinologist and scientist, discusses the growing field of research into the connections between type 1 diabetes (T1D) and osteoporosis.

The Diabetes-Specific Risk-Taking Inventory proved useful in assessing risk-taking behavior in adolescents with type 1 diabetes (T1D), but future research on potential interventions is needed.

Research supports markers like C-peptide not only for the diagnosis of type 1 diabetes (T1D), but also for patient management.

Despite the increased prevalence of insulin pump use over the past 2 decades, there have been few improvements in uptake of the devices among patients who are Black or who come from lower socioeconomic levels.

Findings of a study on children and adolescents with type 1 diabetes (T1D) in Italy suggest lockdown periods during COVID-19 did not increase disordered eating symptoms or adversely affect disease management.

Patients said they benefited from diabetes management technology, but also from social accountability.

Body mass index did not appear to correlate with glycemic control, the study found.

The study suggests blood pressure and cholesterol medications may be appropriate for some younger patients in order to prevent renal complications.

The findings could lead to new insights into how type 1 diabetes develops.