Rheumatology

Treatment options for patients with these rare diseases have expanded in recent years, but rheumatologists may have limited experience with systemic vasculitis.

No clinical or genetic markers were found to be predictive of psoriatic arthritis in patients with psoriasis, but one laboratory marker was identified.

A new review shows secukinumab continued to have a strong safety profile after 6 years on the market.

A systematic review found significant evidence supporting self-management interventions for inflammatory arthritis, but also found it was difficult to draw conclusions about specific types of programs.

The latest news in the rheumatology space revealed potential biomarkers for differentiating psoriatic arthritis (PsA) from rheumatoid arthritis (RA), as well as other rheumatology news reported across MJH Life Sciences™.

Clinical trials and postmarketing surveillance suggest secukinumab has a favorable safety profile and low rates of discontinuation. A new study evaluated those metrics in a real-world setting in axial spondyloarthritis (AxSpA) and psoriatic arthritis (PsA).

About one-third of patients prefer in-hospital administration, particularly if they are older or already make frequent visits to the hospital.

Patients with ankylosing spondylitis taking secukinumab saw improvements in enthesitis, and some achieved complete resolution, suggesting the drug could be a viable option for patients intolerant of or unresponsive to other enthesitis-improving medications.

The studies used population-level data from a county in Minnesota that has served as a national laboratory for health research since the 1960s.

Using a large US database, researchers characterized the impact of psoriatic arthritis (PsA) in patients with disease activity in multiple domains vs those with disease activity affecting a single area.

Methotrexate reduces cardiovascular risk in patients with inflammatory disease but not in the general population.

Birth control guidance provided to women taking rheumatoid arthritis therapies is lacking, and other rheumatology news reported across MJH Life Sciences™.

Ultrasounds and MRI are both used to monitor inflammation activity in rheumatoid arthritis, but their value in refining future treatment strategies has so far been unknown.

Some of the latest rheumatology news includes updates on pregnancy, exercise, and treatment for psoriatic arthritis.

Ankylosing spondylitis (AS) patients face a greater risk of mortality, but treatment with tumor necrosis factor inhibitors erases it.

Using acitretin in combination with secukinumab resulted in nearly complete or total relief for 3 patients with severe psoriasis, according to a case study.

About 90% of patients are diagnosed with rheumatoid arthritis in an outpatient setting, while the 10% diagnosed in an emergency department or as inpatients incur significantly higher health care costs.

A proportion of rheumatoid arthritis pain may be more appropriately considered separate from inflammation and should be treated as a focus of its own.

Guidelines on the use of biologic drugs in patients with psoriasis were mostly seen as having medium-to-high quality; however, investigators said that more work needs to be done to ensure applicability to clinical practice.

Adalimumab was the most commonly used tumor necrosis factor-alpha inhibitor (TNFi), accounting for 47% of 90,000 incidences of TNFi use. Rituximab was the most commonly used non-TNFi, for 44% of 70,000 incidences of non-TNFi use.

Researchers did not find an association in people who had gout.

The risk for patients with monoclonal gammopathy of undetermined significance developing multiple myeloma is double if they have a specific category of rheumatic diseases compared with those without the diseases.

COVID-19 led many patients to change their use of disease-modifying antirheumatic drugs in the pandemic’s initial months, with or without physician guidance.

Behçet disease (BD), a rare systemic inflammatory disease, is associated with multiple sclerosis (MS) and rheumatoid arthritis (RA).

In patients with chronic inflammatory rheumatic and musculoskeletal diseases (RMD), the presence of metabolic syndrome (MetS) indicates an increased risk of cancer.

The bipartisan bill spells out 5 step therapy exemptions for patients by amending the Employee Retirement Income Security Act of 1974.

As the first quarter of 2021 ends, patients choosing to keep using secukinumab may be offered an inducement to switch to another biologic, ixekizumab.

There is a lack of standards for diagnosing and treating nail psoriasis, a situation needing attention because the condition is often a precursor to psoriatic arthritis.

Five biologics used in the treatment of adult patients with plaque psoriasis have been found to improve health-related quality of life.

More real-world evidence is needed to determine what role a score of 100 on the Psoriasis Area and Severity Index (PASI) might have in daily clinical practice, according to a recent review.