Parkinson Disease

Significantly more patients with Parkinson disease (PD) achieved improved motor function and clinical outcomes when treated with high- vs low-dose inhaled levodopa.

Faster motor and cognitive progression of Parkinson disease was found in patients with higher baseline cerebrospinal fluid neurofilament heavy levels.

Angiotensin receptor blockers exhibited potential neuroprotective properties for reducing Parkinson disease (PD) risk in patients with newly diagnosed hypertension.

Advocacy and awareness; prevention and risk reduction; diagnosis, treatment, and care; caregiver support; and research were listed as actionable steps that are urgently needed to address global disparities in Parkinson disease.

Electrical stimulation, physical activity, and balance interventions were also found to be effective in improving gait for patients with neurological disorders including Parkinson disease (PD), stroke, and dementia, according to a recent review.

Rune Labs’ StrivePD software has been granted FDA clearance to collect data for patients with Parkinson disease using the Apple Watch, supporting communication of data between clinicians and patients.

The product, sold as Inbrija, is commercialized in Germany through an agreement with Esteve Pharmaceuticals GmbH.

Levels of the hormone increase with disease severity, a new study has found.

A new study suggests that men who have disturbing dreams more than once a week have a risk that is more than twice as high as the population of developing Parkinson disease (PD).

The findings from the study indicate that higher genetic risk score for Alzheimer disease (AD) are associated with cognitive declines in patients with Parkinson disease (PD), while higher genetic risk scores for PD signify an increased risk of PD, albeit with slower clinical progression after diagnosis.

While the burden on caregivers of family members with neurodegenerative diseases such as Parkinson disease (PD) is well known, data on longitudinal trajectories of this burden are limited; this study followed caregivers for 2 years.

Intensified treatment for Parkinson disease (PD) as noted in patients' electronic medical records can serve as an indicator of more advanced disease.

While periodic limb movements in sleep (PLMS) and restless leg syndrome (RLS) are well-known in Parkinson disease, similar movements during wakefulness are not as well described.

Although patient-centered research is growing, there are no established standards or best practices geared specifically to address the complex nature of individuals living with Parkinson disease (PD) who may want to participate.

Subjective associations of poor sleep are known to be linked with worse health-related quality of life in Parkinson disease, but correlating objective measures are harder to find.

Patients with Parkinson disease (PD) were asked their opinions about which medical services they preferred to use via telehealth and which might be better suited to in-person care.

Recent studies suggest patients with Parkinson disease (PD) suffer from tooth grinding and related pain at higher rates than healthy controls.

Adherence to a Mediterranean diet, which modulates gut microbiota, offers some protection against Alzheimer disease, but results of the review indicated more research is needed to understand the effect on Parkinson disease.

Investigators assessed different machine learning models to see which was best at distinguishing Parkinson disease from essential tremor.

Analyses of blood-based markers showed an association between diabetes and higher glycated hemoglobin with cognitive impairment among those with Parkinson disease.

A review expanded on urological complications associated with Parkinson disease (PD), as well as therapies for these complications.

A recent review highlighted the benefits of conducting further research on surgical disease modification to slow the progression of Parkinson disease.

A recent study found that virtual reality and motor imagery techniques, such as games for the Wii console, can be more helpful for patients with Parkinson disease (PD) than physical therapy.

Using statins led to a lower risk of parkinsonism, according to new research, which also found that statin use had an affect on the buildup of placques in the brain.

A randomized clinical trial examined patient quality of life in Parkinson disease (PD) when adding different adjuvant therapies to levodopa to help control dyskinesia and a flaring of symptoms during OFF periods to see if one drug class had any benefit over another.

This review sought to give more information about the types of treadmill training that might be beneficial for patients with Parkinson disease and other neurological disorders engaged in physical rehabilitation programs.

Parkinson disease is believed to have a prodromal phase, long before neuronal death occurs, and some studies have focused on the gut-brain axis to look for clues.

A recent literature review found that balance training conducted via virtual reality is beneficial at improving symptoms in Parkinson disease.