Inflammation

A higher Dietary Inflammatory Index score was linked to an increased risk of hypertension in children and adolescents, emphasizing the role of diet in blood pressure regulation.

Hispanic and non-White patients with psoriatic arthritis (PsA) had higher tender joint counts and greater disease severity, highlighting racial and ethnic disparities in PsA disease burden and treatment outcomes.

A genetic causal link between rheumatoid arthritis (RA) and an increased risk of traumatic and osteoporotic fractures underscores the need for targeted prevention strategies.

No significant association was found between osteoarthritis and cognitive decline, but depression may influence mental outcomes, particularly in those with vascular dementia.

While higher patient-reported Psoriatic Arthritis (PsA) Impact of Disease questionnaire (PsAID-12) scores were associated with treatment escalation, physicians primarily relied on clinical assessments when making treatment decisions.

This systematic review of real-world observational studies demonstrated the effectiveness of Janus kinase (JAK) inhibitors in improving treatment adherence, persistence, clinical outcomes, and patient-reported outcomes among US patients with rheumatoid arthritis.

Early onset active inflammatory bowel disease (IBD) is associated with significantly higher rates of psychiatric disorders and increased use of psychotropic medications.

Nurse-led care effectively reduces disease activity and improves self-efficacy in patients with rheumatoid arthritis, delivering comparable outcomes to rheumatologist-led care and usual care while easing health care burdens.

Compared with female patients, male patients with eosinophilic esophagitis have higher rates of complications, including esophageal obstruction, food impaction, and rupture, highlighting potential gender differences in disease severity.

The expanded indication makes dupilumab the only approved treatment for eosinophilic esophagitis (EoE) in this age group.

A new study suggests vitamin D2 supplementation on patients with psoriasis is superior to vitamin D3 supplementation, but there was no significant difference in heterogeneity.

In a new study, patients with psoriasis had a 39.46% prevalence of being overweight and 37.41% prevalence of obesity—83.56% patients also dismissed the importance of having healthy balanced eating habits.

This study found no significant associations between weight changes and outcomes in hand osteoarthritis.

This year’s most-read articles on inflammation explored predictive biomarkers, medication acceptance, the impacts of long COVID-19, and more.

This data represented the first-ever research presented at ACR on both fractures and calcium pyrophosphate deposition disease.

A cross-sectional study revealed that neuroinflammation is linked to irritability, among other neuropsychiatric symptoms, in patients with Alzheimer disease (AD).

In a real-world, prospective study, upadacitinib demonstrated great potential for the treatment of rheumatoid arthritis (RA) regardless of a patient’s baseline C-reactive protein (CRP) levels.

New data show one-quarter of patients with kidney disease associated with IBD progress to end-stage disease, with primary determinants including age and baseline eGFR.

Results showed higher-exposure dupilumab met the study’s primary endpoint for peak esophageal intraepithelial count ≤6 eos/high-power field.

Posters presented at the American College of Gastroenterology's (ACG's) 2023 Annual Scientific Meeting examined potential environmental risks of eosinophilic esophagitis (EoE) on the pediatric population, as well as the presence of allergic comorbidities in children diagnosed with EoE.

A co-expression network analysis pinpoints different gene expressions that can potentially predict rheumatoid arthritis (RA) outcomes during pregnancy.

A study from UCSD highlights how advances in imaging modalities and utilization could aid in the early detection of psoriatic arthritis.

If approved, the treatment would be the first of its kind for young children enduring eosinophilic esophagitis (EoE).

Persistent disability and risks of death were associated with inflammatory levels in patients following major abdominal surgery.

Patients with IBD-RA and depression were younger, more likely to be female, and were more frequently White compared with controls.

In a longitudinal case study, researchers found that higher inflammation levels may predict poor outcomes following bariatric surgery.

Adverse effects associated with glucocorticoid use among patients with rheumatoid arthritis may not be as burdensome as previously indicated.

Combination endoscopic sinus surgery (ESS) and biological therapy significantly decreased polyp burden in refractory chronic rhinosinusitis with nasal polyposis (CRSwNP) compared with biologic therapy alone

Through a series of regression analyses, researchers projected the ever-increasing global burden of osteoarthritis (OA) until 2050.