Connor Iapoce is an assistant editor for HCPLive.
Intensive Blood Pressure Regimen Lowers CVD Risk for People With Diabetes
Reducing systolic blood pressure to less than 120 mmHg lowered the risk of major cardiovascular events for most people with type 2 diabetes in the Blood Pressure Control Target in Diabetes trial.
Patient-Reported Outcomes Favor Concizumab Prophylaxis in Hemophilia A or B
Analysis of the phase 3 explorer7 (NCT04083781) study indicates a preference for concizumab prophylaxis over no prophylaxis in patients with hemophilia A or B with inhibitors.
Ravulizumab Boosts Activity Levels, Quality of Life in Patients With PNH
Ravulizumab therapy may enable patients with paroxysmal nocturnal hemoglobinuria (PNH) to comparable achieve activity levels and patient-reported outcomes to the US general population.
COVID-19 Vaccination Shows Favorable Risk-Benefit in Sickle Cell
A study from the American Society of Hematology (ASH) Research Network reports positive antibody response and tolerability after mRNA vaccination in people with sickle cell disease.
Children With Sickle Cell Disease Experience Severe COVID-19 Infection
In a registry-based analysis, more hospitalized children with SCD and COVID-19 had severe infection requiring supplemental oxygen, compared with the general population.
Analysis Shows Association Between Hypothyroidism and T1D
Mendelian randomization analyses demonstrated a causal relationship between hypothyroidism and diabetes, along with its related microvascular complications.
Inflammatory Bowel Disease Associated With Progression to End-Stage Kidney Disease
New data show one-quarter of patients with kidney disease associated with IBD progress to end-stage disease, with primary determinants including age and baseline eGFR.
Smoking Intensity Impacts Choroidal Microvasculature Dropout Area in Glaucoma
Smoking intensity was shown to be associated with larger microvasculature dropout areas in patients with glaucoma, particularly those with more severe disease.
Vosoritide Approved for Achondroplasia in Children Under 5 Years by FDA
Children of all ages with achondroplasia are now included in the expanded Indication, the most common form of skeletal dysplasia leading to disproportionate short stature.
Hybrid Closed-Loop Therapy Effective for Pregnant Women With Type 1 Diabetes
Results from the AiDAPT trial show hybrid closed-loop therapy significantly improves maternal glycemic control during pregnancy complicated by T1D.
FDA Approves Medtronic’s Extravascular Defibrillator for Ventricular Arrhythmia
The first-of-its-kind Aurora EV-ICD system offers a single-device, single procedure with a lead placed outside of the heart and veins.
FDA Grants Priority Review to Sotatercept for Pulmonary Arterial Hypertension
Granted a PDUFA date in March 2024, if approved, sotatercept would be a first-in-class medication to address the rare and progressive disease.
High Blood Pressure in Adolescence Increases Cardiovascular Event Risk, Study Finds
An analysis of more than 1 million men found higher blood pressure in late adolescence was associated with an increased risk for major cardiovascular events in later life.
Historical Redlining Associated With Increased Heart Failure Risk in Black Adults
A new analysis from the American Heart Association found present-day heart failure risk was higher among Black adults who lived in areas historically impacted by redlining.
Modifiable Factors Influence Racial, Ethnic Differences in PWV in Youth With T1D
A recent analysis suggests that cardiovascular and socioeconomic factors explain one‐quarter of the racial and ethnic differences in arterial stiffness of youth with type 1 diabetes.
Older Individuals With Hyperopia More Likely to Develop Incident Depression
Genetic factors previously known to predispose people to hyperopia were not risk factors for clinically significant depression in the study.
Mental Health Disparities Observed in People With Diabetes Across Europe
People with diabetes in Italy and the United Kingdom reported the highest rates of anxiety at 63% and 51%, respectively.