Panelists explore opportunities for biosimilars to manage inflammatory conditions.
This is a video synopsis/summary of a panel discussion involving Ryan Haumschild, PharmD, MS, MBA; Alice B. Gottlieb, MD, PhD; Bincy Abraham, MD, MS; Jamie T. Brogan, APRN; and Vibeke Strand, MD.
Haumschild asked Brogan about the key opportunities provided by biosimilars for inflammatory conditions, specifically seeking her insights on opportunities around adalimumab (Humira) biosimilar access and use for providers and payers.
Brogan responded that biosimilars provide cost savings opportunities through competition, which could free up health care dollars for other needed treatments. The VOLTAIRE trials with adalimumab biosimilar BI 695501 (adalimumab-adbm, Cyltezo; Boehringer Ingelheim) included Crohn disease patients, providing indication-specific data to reassure providers. From the payer perspective, adalimumab biosimilar competition allows price negotiations and access to discounts off the originator price. Payers will need to adapt formularies and provide education to ensure successful adoption.
Haumschild agreed cost savings would be beneficial, but noted provider concerns around immunogenicity, switching limits, and product differences that require thoughtful education so that patients understand without getting overwhelmed.
Video synopsis is AI-generated and reviewed by AJMC editorial staff.
Niraparib Extends PFS, Time to Next Treatment in Patients With EOC, Especially BRCA-Mutated Cases
January 28th 2025First-line maintenance (1LM) niraparib significantly extends progression-free survival (rwPFS) and time to next treatment (rwTTNT) in patients with epithelial ovarian cancer (EOC), with the greatest benefit observed in those considered homologous recombination-deficient (HRd) and those with BRCA-mutated (BRCAm) tumors.
Read More
FDA Approves New Maintenance Dosing for Lecanemab to Treat Early-Stage Alzheimer Disease
January 27th 2025The FDA approves a new maintenance dosing regimen for lecanemab (Leqembi; Eisai) in patients with early-stage Alzheimer disease (AD), enabling a transition from biweekly to once-every-4-week dosing while preserving clinical and biomarker benefits.
Read More