Decision-Making Process Surrounding Biosimilar Implementation

EP: 1.Utilizing Recently Approved Biosimilars in Clinical Practice

EP: 2.Transitioning to Biosimilars: Considerations for Providers and Payers

EP: 3.Navigating Challenges Associated with Biosimilars Across Various Disease States

EP: 4.Provider Acceptance Driving Confidence in Biosimilar Therapy

Now Viewing

EP: 5.Decision-Making Process Surrounding Biosimilar Implementation

EP: 6.Biosimilar Administration Considerations Impacting Patient Experience

EP: 7.Initiating Biosimilar Treatment in Patients Without Previous Reference Biologic Experience

EP: 8.Switching Patients from Reference Product to Biosimilar

EP: 9.Defining Interchangeability and Switching in Biologics

EP: 10.Evolution of Auto-Substitution in Biosimilar Landscape

EP: 11.An Overview of Biosimilar Extrapolation During FDA Approval

EP: 12.Harnessing Indication-Specific Data on Biosimilars

EP: 13.Cost Savings Related to Biosimilars

EP: 14.Payers and PBMs Impacted by Biosimilar Integration

EP: 15.Payer Support Driving Lowering of Biosimilar-Related Health Care Costs

EP: 16.Patient Conversations: Managing Patient Expectations Regarding Biosimilars

EP: 17.Key Points of Emphasis Regarding Biosimilar Integration

This is a video synopsis/summary of a panel discussion involving Ryan Haumschild, PharmD, MS, MBA; Alice B. Gottlieb, MD, PhD; Bincy Abraham, MD, MS; Jamie T. Brogan, APRN; and Vibeke Strand, MD.

Haumschild asked Gottlieb how she navigates choosing between a biosimilar or reference product for patients.

Gottlieb said most dermatologists prefer the reference adalimumab (Humira) given familiarity, as they lack education on biosimilar approval and interchangeability. She strongly prefers a biosimilar with interchangeability data and wants to know when patients switch. She would appeal for an interchangeable biosimilar over one without data. She also prefers a biosimilar studied in the disease being treated due to different outcomes and doses.

Strand disagreed, noting rheumatology patients frequently switch medications. Adalimumab is usually the first biologic, but then providers tend to switch to another agent after failure. Biosimilars will likely be first-line treatment, with little provider choice. Though interchangeability data is preferable, current biosimilars are highly similar without it. Providers rarely switch within a class, which limits adalimumab biosimilar opportunities. Prior authorizations are frustrating and may limit choices among the many adalimumab biosimilars.

Haumschild agreed providers should help select preferred therapies and interchangeable options. Provider comfort varies, but experience over time increases acceptance, as with bevacizumab.

Video synopsis is AI-generated and reviewed by AJMC editorial staff.