A panel of experts on Alzheimer disease provide insights on symptoms the patient might experience and the impact of the disease on patients, families, caregivers, and the health care system.
Please describe the clinical impact of AD in terms of symptoms the patient might experience before diagnosis and the progression of symptoms over time, and how this impacts not only the patient, but families/caregivers and the healthcare system.
What is the impact of AD in terms of costs related to diagnosis and treatment, and how this impacts society at large?
Discuss the genetic factors associated with AD. How do mutations in genes such as APP, PSEN1, and PSEN2 contribute to the pathophysiology of the disease? How do different alleles of APOE4affect risk of developing AD?