Supporting Ph+ ALL Patient: Emotional Challenges and Quality of Life

EP: 1.Overview of Characteristics Unique to Ph+ ALL

EP: 2.Timely Detection: Incidence and Prevalence of Ph+ ALL

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EP: 3.Supporting Ph+ ALL Patient: Emotional Challenges and Quality of Life

EP: 4.Screening and Diagnosing of Ph+ ALL in Adults

EP: 5.Diagnosis and Treatment Timeline: Different Phases of Ph+ ALL Management

EP: 6.Current Front-Line Targeted Treatments in Ph+ ALL

EP: 7.Prior Authorization and Access to Targeted Treatment for Ph+ ALL Patients

EP: 8.PhALLCON Trial: Efficacy and Safety of Ponatinib in Ph+ ALL Patients

EP: 9.Value-Based Care Models Optimizing Ph+ ALL Patient Care

EP: 10.Unmet Needs in Screening, Diagnosis, and Management of Ph+ ALL

EP: 11.Disparities in Access to Care for Ph+ ALL patients

EP: 12.The Future of Ph+ ALL Treatments

EP: 13.Concluding Thoughts on Ph+ ALL Treatment

The following is a video synopsis/summary of a Peer Exchange involving Ryan Haumschild, PharmD, MS, MBA, CPEL; Jonathon Abbas, MD; Vivian Tambe Tar, PharmD, MBA; Elias Jabbour, MD; and James McCloskey, MD.

The discussants focus on the impact of Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) and its treatment relating to patients' quality of life (QOL) and emotional well-being. Abbas noted the wide variation in patient age, from teenagers to octogenarians, each requiring personalized supportive care. The typically months-long treatment regimens with frequent clinic visits can be burdensome, especially for younger patients who may be building careers or families. Haumschild emphasized considering QOL goals, such as the ability to work and maintain mental health and relationships with loved ones. Monitoring QOL and adjusting care accordingly should be part of the treatment approach. The toxicity burden and its impact also require special attention in older patients with comorbidities. Overall, supporting patients with Ph+ ALL holistically emerges as a key priority.

Video synopsis is AI-generated and reviewed by AJMC editorial staff.