Medical doctors discuss the future of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) and their five-year outlook for advancements and potential cures for the disease.
This is a video synopsis/summary of a Peer Exchange involving: Ryan Haumschild, PharmD, MS, MBA; Jonathan Abbas, MD; Elias Jabbour, MD; James K. McCloskey, MD; Vivian Tambe Ebot-Tar, PharmD, MBA.
In conclusion, Dr Abbas stressed engaging community practices more in Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) care while ensuring specialist leadership and optimal up-front therapy access. Dr Jabbour highlighted immense survival gains from 10% to 90% in recent years, with cures becoming reality now—not just ideals for the future. Equity in access to best available treatments remains vital. Dr McCloskey advised rethinking outdated potent toxicity perceptions given new safety data enabling more appropriate patient selection. Robust measurable residual disease monitoring must inform Ph+ ALL management everywhere. Dr Ebot-Tar discussed payers balancing innovation support, value demonstration to stakeholders, and personalized care. Ongoing collaboration between specialties and health plans can continue progress.
Video synopsis is AI-generated and reviewed by AJMC® editorial staff.
High HSP60 Expression Signals Poor Prognosis, Aggressive Tumors in Ovarian Cancer
January 16th 2025High heat shock protein 60 (HSP60) expression in patients with ovarian cancer is associated with larger tumors, advanced stages, and worse survival outcomes, highlighting its potential as a prognostic biomarker.
Read More
Real-World Evidence Confirms the Benefits of JAK Inhibitors in Patients With Rheumatoid Arthritis
January 16th 2025This systematic review of real-world observational studies demonstrated the effectiveness of Janus kinase (JAK) inhibitors in improving treatment adherence, persistence, clinical outcomes, and patient-reported outcomes among US patients with rheumatoid arthritis.
Read More