- Center on Health Equity & Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Key Highlights From ASH 2023
Dr Haumschild drives a discussion surrounding the role of bruton kinase inhibitors for treating CLL and SLL.
EP: 1.Clinical Characteristics Distinguishing CLL and SLL
EP: 2.Quality of Life Impacted By CLL and SLL Diagnosis and Management
EP: 3.Evaluating Current Treatment Landscape of CLL and SLL
EP: 4.Unmet Needs In CLL and SLL Treatment Management
EP: 5.Indications and Considerations For BTK Inhibitor Use In CLL and SLL Management
EP: 6.Examining Safety and Efficacy of BTK Inhibitors In CLL and SLL Treatment
EP: 7.Determining Optimal CLL / SLL Therapy: Ibrutinib, Acalabrutinib and Zanubrutinib
EP: 8.Key Highlights From ASH 2023
EP: 9.Economic Burden Associated With BTK Inhibitor Use
EP: 10.Patient Education Driving BTK Inhibitor Treatment Adherence
EP: 11.Optimizing BTKi Treatment Strategies
EP: 12.Key Considerations for Treating Patients Diagnosed With CLL and SLL
This is a video synopsis/summary of a Peer Exchange involving Ryan Haumschild, PharmD, MS, MBA, CPEL; Tara Graff, DO, MS; Ryan Jacobs, MD; Deborah Stephens, DO; and Jennifer Woyach, MD.
The group discusses anticipated data on Bruton tyrosine kinase (BTK) inhibitors presented at the 2023 American Society of Hematology (ASH) annual meeting. Dr Jacobs highlights the updated results from the ALPINE trial comparing zanubrutinib to ibrutinib in relapsed/refractory chronic lymphocytic leukemia (CLL). The initial late-breaking results presented at ASH 2022 showed zanubrutinib had an improved safety profile and progression-free survival benefit over ibrutinib. The updated 1-year follow-up data presented at ASH 2023 confirm this progression-free survival difference has been maintained.
Dr Jacobs notes this updated data help reaffirm the efficacy differences seen between the next-generation BTK inhibitors like zanubrutinib and the original BTK inhibitor ibrutinib. ASH provides an opportunity to see the latest clinical trial results with these novel agents and how they may change treatment approaches for diseases like CLL and small lymphocytic lymphoma going forward.
Video synopsis is AI-generated and reviewed by AJMC® editorial staff.
Racial Differences in CA-125 Levels Tied to Ovarian Cancer Treatment Delays
April 17th 2025Black and American Indian women with ovarian cancer were less likely to have elevated cancer antigen 125 (CA-125) levels at diagnosis, resulting in delayed chemotherapy initiation and highlighting the need for more inclusive guidelines.
Read More
SGLT2 Inhibitors Show Renal Benefits in HF and CKD as Prescribers Target Uptake Gaps
April 15th 2025Abstracts featured at the National Kidney Foundation Spring Clinical Meeting highlighted the renoprotective benefits of SGLT2 inhibitors in heart failure and diabetic kidney disease while emphasizing the need for strategies to increase their uptake in primary care.
Read More
