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Tim Mok, PharmD, BCPS, BCOP, malignant hematology pharmacy research analyst at Kaiser Permanente, discussed his perspective on the balance between clinical outcomes and cost considerations. 

Dr Tim Mok: A Pharmacist's Perspective on Balancing Costs and Outcomes

Skylar is an associate editor for The American Journal of Managed Care® (AJMC®) and The Center for Biosimilars®, and joined AJMC® in 2020. She is responsible for covering all aspects of the ever-changing global biosimilar industry and produces content that is accessible and informative for all health care stakeholders.

She has a BA in journalism and media studies from Rutgers University. You can connect with Skylar on 

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Tiago Biachi, MD, PhD, discusses the challenges of treating gastrointestinal (GI) cancers, particularly the limited effectiveness of immunotherapy for "cold tumors" and the need to make them more responsive to immune treatments.

Empowering Patients With GI Cancer: Overcoming Immunotherapy Limitations

Jared is a freelance writer for The American Journal of Managed Care® (AJMC®), and previously worked as a senior editor for HCPLive® at MJH Life Sciences®.

He has an MA from University of Sioux Falls. You can connect with Jared on 

Patients with generalized myasthenia gravis experienced durable improvements across measures of efficacy and regardless of the time since they were diagnosed. 

Efgartigimod Leads to Sustained Myasthenia Gravis Improvement

A Mendelian analysis supports the idea that hyperuricemia may be an important risk factor for pulmonary arterial hypertension (PAH). 

High Uric Acid Appears to Have Causal Role in PAH

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Exploring Novel Treatment Options for Alopecia Areata

Video Series

Common Comorbidities Associated With Alopecia Areata

Video content above is prompted by the following:

Mostaghimi: What are the concurrent comorbidities commonly seen in patients with AA?

How do they contribute to the burden of disease?

How do these affect your management plan?

Panelists discuss how recent advancements, particularly the introduction of Janus kinase JAK inhibitors, are reshaping the treatment landscape for Aalopecia Aareata, offering new therapeutic options and addressing unmet needs in both efficacy and patient care.

Panelists discuss how alopecia areata (AA) is a chronic autoimmune disease characterized by inflammation that attacks hair follicles, leading to hair loss and varying disease progression.

Discussing the Pathophysiology of Alopecia Areata

Panelists discuss how the epidemiology of alopecia areata (AA) varies across different patient populations, with certain forms of the disease being more prevalent in specific groups.

Epidemiology Associated With Alopecia Areata

Panelists discuss how concurrent comorbidities, such as thyroid disorders and other autoimmune conditions, are commonly seen in patients with alopecia areata (AA) and how they complicate disease management and increase the overall burden on patients.

Panelists discuss how alopecia areata (AA) presents with hallmark symptoms such as sudden hair loss, and how the condition fluctuates over time, making it a relapsing or remitting inflammatory disease.

Hallmark Symptoms Seen With Alopecia Areata

Panelists discuss how ongoing or recurrent hair loss in patients with alopecia areata (AA) leads to significant psychological effects, impacting their mental health, and how different forms of AA may be harder for some patients to cope with, with strategies for managing these psychological challenges in clinical practice.

Psychosocial Impact of Alopecia Areata

Alopecia areata (AA) is a chronic autoimmune disorder characterized by non-scarring hair loss, primarily due to the immune system's attack on hair follicles. The pathophysiology involves a breakdown in immune privilege of hair follicles, leading to an inflammatory response. Cytotoxic T cells, particularly CD8+ T cells, infiltrate the hair follicle, causing hair loss. Inflammation plays a crucial role, with cytokines such as IFN-γ and TNF-α contributing to the immune-mediated destruction of hair follicles. The chronic nature of AA is attributed to persistent immune dysregulation and genetic predisposition.

Common Comorbidities Associated With Alopecia Areata

EP: 1.Discussing the Pathophysiology of Alopecia Areata

EP: 2.Epidemiology Associated With Alopecia Areata

EP: 3.Common Comorbidities Associated With Alopecia Areata

EP: 4.Hallmark Symptoms Seen With Alopecia Areata

EP: 5.Psychosocial Impact of Alopecia Areata