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Applying Trial Data to Real-World Practice in ALK+ NSCLC
Panelists discuss how clinical trial outcomes like CROWN and eXalt3 reflect real-world patient experiences and how these collective data have changed perspectives on frontline therapies for ALK+ non–small cell lung cancer (NSCLC).
Real-World Settings and Evolution of Frontline Therapy
Key Themes:
- Comparison of clinical trial outcomes to real-world patient experiences
- Impact of clinical data (ALINA, CROWN, eXalt3) on frontline therapy choices
- Evolving perspective on frontline therapies for ALK+ NSCLC
Notable Insights:
- Grizzard addressed how well outcomes from trials like CROWN and eXalt3 reflect real-world patient experiences
Dr Dietrich summarized how recent clinical data has changed the landscape of frontline therapies for ALK+ NSCLC
For Patients Who Cannot Wait, This Off-the-Shelf CAR NK Treatment for AML Leaves Healthy Cells Alone
May 12th 2025First part of a 2-part interview with Stephen Strickland, MD, MSCI, director of leukemia research for Sarah Cannon Research Institute. Strickland recently presented data from a phase 1 trial of SENTI-202, an investigational chimeric antigen receptor (CAR) natural killer (NK) cell therapy.
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